MolNFT v1 · #470942 · protein
AlphaFold monomer V2.0 prediction for triosephosphate isomerase (P60174)
P60174: “AlphaFold monomer V2.0 prediction for triosephosphate isomerase (P60174)”. 2 pockets (best druggability 0.39). MolNFT v1 #470942 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P60174
- Type
- protein
- Length
- 249 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd10960F956646DE8b64d3598984c91C2d5Af3D7b
- Molecule
- Triosephosphate isomerase
- UniProt
- P60174
- Pockets
- 2 · best druggability 0.39
Structure
1 distinct chain · 44% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Triosephosphate isomerase | protein | 249 | 44% helix, 16% strand | P60174 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 106 | 0.39 | 0.76 | 16 | empty |
| 2 | 51 | 0.36 | 0.80 | 19 | empty |
Compared structures
- 6UPF · Triosephosphate isomerase deficiency: Effect of F240L mutation on enzyme structure · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 6UPF · Triosephosphate isomerase deficiency: effect of F240L mutation on enzyme structure · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 6UP5 · Triosephosphate isomerase deficiency: effect of F240L mutation on enzyme structure · an experimental structure of the same protein · chain A against B, TM-score 0.99
- 6UP5 · Triosephosphate isomerase deficiency: Effect of F240L mutation on enzyme structure · an experimental structure of the same protein · chain A against B, TM-score 0.99
- 4POC · Structure of triosephosphate isomerase wild type human enzyme. · an experimental structure of the same protein · chain A against B, TM-score 0.99
- 4POC · Structure of Triosephosphate Isomerase Wild Type human enzyme. · an experimental structure of the same protein · chain A against B, TM-score 0.99
- 4POD · Structure of triosephosphate isomerase I170V mutant human enzyme. · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 4POD · Structure of Triosephosphate Isomerase I170V mutant human enzyme. · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 7UXV · human triosephosphate isomerase mutant G122R · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 4ZVJ · Structure of human triose phosphate isomerase K13M · an experimental structure of the same protein · chain A against B, TM-score 0.98
- 4ZVJ · Structure of human triose phosphate isomerase K13M · an experimental structure of the same protein · chain A against B, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P60174
- Elsewhere: UniProt P60174 · AlphaFold DB P60174
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