MolNFT v1 · #188717 · protein
Il-27 quaternary receptor signaling complex
7U7N: “Il-27 quaternary receptor signaling complex”. Electron microscopy, 3 ligands (NAG, BMA, MAN). MolNFT v1 #188717 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7U7N
- Type
- protein
- Length
- 884 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q6UWB1, P40189, Q14213, Q8NEV9
- Ligands
- NAG, BMA, MAN
Structure
electron microscopy · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 195 | — | Q6UWB1 |
| B | — | protein | 298 | — | P40189 |
| C | — | protein | 200 | — | Q14213 |
| D | — | protein | 191 | — | Q8NEV9 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 12 copies · chains B, C, A
- BMA · beta-D-mannopyranose · sugar · 3 copies
- MAN · alpha-D-mannopyranose · sugar
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7U7N · IL-27 quaternary receptor signaling complex · the same entry in another collection · chain D against D, TM-score 1.00
- Q14213 · AlphaFold monomer V2.0 prediction for interleukin-27 subunit beta (Q14213) · a predicted model of the same protein · chain C against A, TM-score 0.97
- Q6UWB1 · AlphaFold monomer V2.0 prediction for interleukin-27 receptor subunit alpha (Q6UWB1) · a predicted model of the same protein · chain A against A, TM-score 0.95
- P40189 · AlphaFold monomer V2.0 prediction for interleukin-6 receptor subunit beta (P40189) · a predicted model of the same protein · chain B against A, TM-score 0.95
- Q8NEV9 · AlphaFold monomer V2.0 prediction for interleukin-27 subunit alpha (Q8NEV9) · a predicted model of the same protein · chain D against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6UWB1
- Every structure of UniProt P40189
- Every structure of UniProt Q14213
- Every structure of UniProt Q8NEV9
- Elsewhere: RCSB PDB 7U7N · PDBe 7U7N · UniProt Q6UWB1 · UniProt P40189 · UniProt Q14213 · UniProt Q8NEV9
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