UniProt Q14213
Interleukin-27 subunit beta (Q14213)
Interleukin-27 subunit beta (UniProt Q14213): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q14213
- Protein
- Interleukin-27 subunit beta
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 16 · 3 records with a druggable one
Structures
5 records of Q14213 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7U7N | IL-27 quaternary receptor signaling complex | electron microscopy | C | NAG | 5 (best 0.72) |
| 7U7N | Il-27 quaternary receptor signaling complex | electron microscopy | C | NAG | — |
| 7ZXK | Human IL-27 in complex with neutralizing SRF388 FAb fragment | x-ray diffraction | B, D | NAG | 4 (best 0.56) |
| 8D85 | Cryo-EM structure of human IL-27 signaling complex: model containing the interaction core region | electron microscopy | C | NAG | 7 (best 0.72) |
| Q14213 | AlphaFold monomer V2.0 prediction for interleukin-27 subunit beta (Q14213) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
Experiment against prediction
- 7ZXK chain D against the predicted model Q14213: TM-score 0.98, RMSD 0.85 Å
- 7U7N chain C against the predicted model Q14213: TM-score 0.97, RMSD 1.06 Å
- 7U7N chain C against the predicted model Q14213: TM-score 0.97, RMSD 1.06 Å
- 7ZXK chain B against the predicted model Q14213: TM-score 0.97, RMSD 1.11 Å
- 8D85 chain C against the predicted model Q14213: TM-score 0.95, RMSD 1.34 Å
Elsewhere
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