UniProt Q8NEV9
Interleukin-27 subunit alpha (Q8NEV9)
Interleukin-27 subunit alpha (UniProt Q8NEV9): 4 experimental structures and 1 predicted model on GenesisL1, 27 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8NEV9
- Protein
- Interleukin-27 subunit alpha
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 27 · 3 records with a druggable one
Structures
5 records of Q8NEV9 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7U7N | IL-27 quaternary receptor signaling complex | electron microscopy | D | — | 7 (best 0.72) |
| 7U7N | Il-27 quaternary receptor signaling complex | electron microscopy | D | — | — |
| 7ZXK | Human IL-27 in complex with neutralizing SRF388 FAb fragment | x-ray diffraction | A, C | — | 9 (best 0.56) |
| 8D85 | Cryo-EM structure of human IL-27 signaling complex: model containing the interaction core region | electron microscopy | D | — | 11 (best 0.72) |
| Q8NEV9 | AlphaFold monomer V2.0 prediction for interleukin-27 subunit alpha (Q8NEV9) | predicted | A | — | — |
Experiment against prediction
- 7U7N chain D against the predicted model Q8NEV9: TM-score 0.92, RMSD 1.71 Å
- 7U7N chain D against the predicted model Q8NEV9: TM-score 0.92, RMSD 1.71 Å
- 8D85 chain D against the predicted model Q8NEV9: TM-score 0.91, RMSD 1.87 Å
- 7ZXK chain A against the predicted model Q8NEV9: TM-score 0.89, RMSD 2.03 Å
- 7ZXK chain C against the predicted model Q8NEV9: TM-score 0.88, RMSD 2.03 Å
Elsewhere
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