UniProt Q6UWB1
Interleukin-27 receptor subunit alpha (Q6UWB1)
Interleukin-27 receptor subunit alpha (UniProt Q6UWB1): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6UWB1
- Protein
- Interleukin-27 receptor subunit alpha
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 11 · 2 records with a druggable one
Structures
5 records of Q6UWB1 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7T5M | Structure of HLA-A*02:01-FLPTPEELGLLGPPRPQVLA complex | x-ray diffraction | E, F | MG | — |
| 7U7N | IL-27 quaternary receptor signaling complex | electron microscopy | A | NAG | 4 (best 0.72) |
| 7U7N | Il-27 quaternary receptor signaling complex | electron microscopy | A | NAG | — |
| 8D85 | Cryo-EM structure of human IL-27 signaling complex: model containing the interaction core region | electron microscopy | A | NAG | 7 (best 0.71) |
| Q6UWB1 | AlphaFold monomer V2.0 prediction for interleukin-27 receptor subunit alpha (Q6UWB1) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7U7N chain A against the predicted model Q6UWB1: TM-score 0.95, RMSD 1.31 Å
- 7U7N chain A against the predicted model Q6UWB1: TM-score 0.95, RMSD 1.31 Å
- 8D85 chain A against the predicted model Q6UWB1: TM-score 0.91, RMSD 1.69 Å
- 7T5M chain F against the predicted model Q6UWB1: TM-score 0.39, RMSD 2.32 Å
- 7T5M chain E against the predicted model Q6UWB1: TM-score 0.36, RMSD 2.31 Å
Elsewhere
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