GL1X · GenesisL1 explorer

MolNFT v1 · #188572 · protein

Calcitonin receptor in complex with gs and salmon calcitonin peptide

7TYN: “Calcitonin receptor in complex with gs and salmon calcitonin peptide”. Electron microscopy, 5 ligands (PLM, P42, Y01). MolNFT v1 #188572 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7TYN
Type
protein
Length
1,154 residues
Chains
6
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
B5XGR7, P30988, P63092, P62873, P59768
Ligands
PLM, P42, Y01, NAG, NH2

Structure

electron microscopy · 6 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
P—protein32—B5XGR7
R—protein373—P30988
A—protein227—P63092
B—protein339—P62873
G—protein55—P59768
N—protein128——

Ligands and binding sites

  • PLM · Palmitic acid · ligand · 13 copies · chains R
  • P42 · (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate · ligand · chains R
  • Y01 · Cholesterol hemisuccinate · ligand · chains R
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains R
  • NH2 · Amino group · ion · chains P, R

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7TYN · Calcitonin Receptor in complex with Gs and salmon calcitonin peptide · the same entry in another collection · chain N against N, TM-score 1.00
  • P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 1.00
  • P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.94
  • P30988 · AlphaFold monomer V2.0 prediction for calcitonin receptor (P30988) · a predicted model of the same protein · chain R against A, TM-score 0.88

Analyse

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