MolNFT v1 · #188409 · protein + RNA

Cryoem structure of the human 40S small ribosomal subunit in complex with translation initiation factors EIF1A and EIF5B.

7TQL: “Cryoem structure of the human 40S small ribosomal subunit in complex with translation initiation factors…”. Electron microscopy, 2 ligands (GNP, ZN). MolNFT v1 #188409 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7TQL
Type: protein + RNA
Length: 7,240 residues
Chains: 38
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: O60841, P15880, P62701, P23396, P62753, P62081, P62241, P46781, P46782, P62280, A0A2R8Y7H1, P62841, P62249, P39019, P62244, P62266, P62847, P63220, P42677, P62854, P62979, P63244
Ligands: GNP, ZN

Structure

electron microscopy · 38 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
1	—	protein	619	—	O60841
2	—	rna	1656	—	—
3	—	rna	76	—	—
4	—	protein	90	—	—
B	—	protein	206	—	—
C	—	protein	213	—	—
D	—	protein	218	—	P15880
E	—	protein	258	—	P62701
F	—	protein	225	—	P23396
G	—	protein	226	—	P62753
H	—	protein	185	—	P62081
I	—	protein	205	—	P62241
J	—	protein	180	—	P46781
K	—	protein	189	—	P46782
L	—	protein	147	—	P62280
M	—	protein	97	—	A0A2R8Y7H1
N	—	protein	141	—	—
O	—	protein	120	—	—
P	—	protein	134	—	—
Q	—	protein	115	—	P62841
R	—	protein	139	—	P62249
S	—	protein	132	—	—
T	—	protein	140	—	—
U	—	protein	139	—	P39019
V	—	protein	101	—	—
W	—	protein	129	—	P62244
X	—	protein	141	—	P62266
Y	—	protein	123	—	P62847
Z	—	protein	82	—	P63220
a	—	protein	72	—	—
b	—	protein	82	—	P42677
c	—	protein	99	—	P62854
d	—	protein	58	—	—
e	—	protein	51	—	—
f	—	protein	54	—	—
g	—	protein	65	—	P62979
h	—	protein	19	—	—
j	—	protein	314	—	P63244

Ligands and binding sites

GNP · Phosphoaminophosphonic acid-guanylate ester · ligand · chains 1
ZN · Zinc ion · metal · 3 copies · chains c, f, g

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7TQL · CryoEM structure of the human 40S small ribosomal subunit in complex with translation… · the same entry in another collection · chain H against H, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O60841
Every structure of UniProt P15880
Every structure of UniProt P62701
Every structure of UniProt P23396
Every structure of UniProt P62753
Every structure of UniProt P62081
Every structure of UniProt P62241
Every structure of UniProt P46781
Every structure of UniProt P46782
Every structure of UniProt P62280
Every structure of UniProt A0A2R8Y7H1
Every structure of UniProt P62841
Every structure of UniProt P62249
Every structure of UniProt P39019
Every structure of UniProt P62244
Every structure of UniProt P62266
Every structure of UniProt P62847
Every structure of UniProt P63220
Every structure of UniProt P42677
Every structure of UniProt P62854
Every structure of UniProt P62979
Every structure of UniProt P63244
Elsewhere: RCSB PDB 7TQL · PDBe 7TQL · UniProt O60841 · UniProt P15880 · UniProt P62701 · UniProt P23396 · UniProt P62753 · UniProt P62081 · UniProt P62241 · UniProt P46781 · UniProt P46782 · UniProt P62280 · UniProt A0A2R8Y7H1 · UniProt P62841 · UniProt P62249 · UniProt P39019 · UniProt P62244 · UniProt P62266 · UniProt P62847 · UniProt P63220 · UniProt P42677 · UniProt P62854 · UniProt P62979 · UniProt P63244

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