MolNFT v1 · #187079 · protein
Isoproterenol bound BETA1 adrenergic receptor in complex with heterotrimeric gi protein
7S0F: “Isoproterenol bound BETA1 adrenergic receptor in complex with heterotrimeric gi protein”. Electron microscopy, 1 ligand (5FW). MolNFT v1 #187079 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7S0F
- Type
- protein
- Length
- 892 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P62871, P10824, P63212
- Ligands
- 5FW
Structure
electron microscopy · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| R | — | protein | 272 | — | — |
| B | — | protein | 338 | — | P62871 |
| A | — | protein | 222 | — | P10824 |
| G | — | protein | 60 | — | P63212 |
Ligands and binding sites
- 5FW · Isoprenaline · ligand · chains R
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7S0F · Isoproterenol bound beta1 adrenergic receptor in complex with heterotrimeric Gi protein · the same entry in another collection · chain R against R, TM-score 1.00
- P62871 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
- P10824 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I) subunit… · a predicted model of the same protein · chain A against A, TM-score 0.83
- P63212 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.63
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62871
- Every structure of UniProt P10824
- Every structure of UniProt P63212
- Elsewhere: RCSB PDB 7S0F · PDBe 7S0F · UniProt P62871 · UniProt P10824 · UniProt P63212
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