UniProt P62871
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (P62871)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (UniProt P62871): 102 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 153 pockets. Binding sites, druggability and experiment against…
- UniProt
- P62871
- Protein
- Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
- Experimental structures
- 102
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 153 · 23 records with a druggable one
Structures
103 records of P62871 in the MolNFT archive: 102 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1B9X | Structural analysis of phosducin and its phosphorylation-regulated interaction with transducin | x-ray diffraction | A | — | — |
| 1B9X | Structural analysis of phosducin and its phosphorylation-regulated interaction with transducin | x-ray diffraction | A | — | — |
| 1B9Y | Structural analysis of phosducin and its phosphorylation-regulated interaction with transducin… | x-ray diffraction | A | — | — |
| 1B9Y | Structural analysis of phosducin and its phosphorylation-regulated interaction with transducin… | x-ray diffraction | A | — | — |
| 1GG2 | G protein heterotrimer mutant GI_ALPHA_1(G203A) BETA_1 GAMMA_2 with GDP bound | x-ray diffraction | B | — | — |
| 1GG2 | G protein heterotrimer mutant GI_ALPHA_1(G203A) BETA_1 GAMMA_2 with GDP bound | x-ray diffraction | B | — | — |
| 1GOT | Heterotrimeric complex of a gt-ALPHA/GI-alpha chimera and the gt-beta-gamma subunits | x-ray diffraction | B | — | — |
| 1GOT | Heterotrimeric complex of a gt-ALPHA/GI-alpha chimera and the gt-beta-gamma subunits | x-ray diffraction | B | — | — |
| 1GP2 | G protein heterotrimer GI_ALPHA_1 BETA_1 GAMMA_2 with GDP bound | x-ray diffraction | B | — | — |
| 1GP2 | G protein heterotrimer GI_ALPHA_1 BETA_1 GAMMA_2 with GDP bound | x-ray diffraction | B | — | — |
| 1OMW | Crystal Structure of the complex between G Protein-Coupled Receptor Kinase 2 and Heterotrimeric G… | x-ray diffraction | B | — | — |
| 1OMW | Crystal structure of the complex between G protein-coupled receptor kinase 2 and heterotrimeric G… | x-ray diffraction | B | — | — |
| 1XHM | The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma… | x-ray diffraction | A | — | — |
| 1XHM | The crystal structure of a biologically active peptide (sigk) bound to a G protein BETA:GAMMA… | x-ray diffraction | A | — | — |
| 2BCJ | Crystal Structure of G Protein-Coupled Receptor Kinase 2 in Complex with Galpha-q and Gbetagamma… | x-ray diffraction | B | — | — |
| 2BCJ | Crystal structure of G protein-coupled receptor kinase 2 in complex with galpha-Q and gbetagamma… | x-ray diffraction | B | — | — |
| 2TRC | PHOSDUCIN/TRANSDUCIN beta-gamma complex | x-ray diffraction | B | — | — |
| 2TRC | PHOSDUCIN/TRANSDUCIN beta-gamma complex | x-ray diffraction | B | — | — |
| 3AH8 | Structure of heterotrimeric G protein Galpha-q beta gamma in complex with an inhibitor YM-254890 | x-ray diffraction | B | — | — |
| 3AH8 | Structure of heterotrimeric G protein galpha-Q beta gamma in complex with an inhibitor ym-254890 | x-ray diffraction | B | — | — |
| 3CIK | Human GRK2 in Complex with Gbetagamma subunits | x-ray diffraction | B | — | — |
| 3CIK | Human GRK2 in complex with gbetagamma subunits | x-ray diffraction | B | — | — |
| 3KRW | Human GRK2 in complex with Gbetgamma subunits and balanol (soak) | x-ray diffraction | B | — | — |
| 3KRW | Human GRK2 in complex with gbetgamma subunits and balanol (soak) | x-ray diffraction | B | — | — |
| 3KRX | Human GRK2 in complex with Gbetgamma subunits and balanol (co-crystal) | x-ray diffraction | B | — | — |
| 3KRX | Human GRK2 in complex with gbetgamma subunits and balanol (co-crystal) | x-ray diffraction | B | — | — |
| 3PSC | Bovine GRK2 in complex with Gbetagamma subunits | x-ray diffraction | B | — | — |
| 3PSC | Bovine GRK2 in complex with gbetagamma subunits | x-ray diffraction | B | — | — |
| 3PVU | Bovine GRK2 in complex with Gbetagamma subunits and a selective kinase inhibitor (CMPD101) | x-ray diffraction | B | — | — |
| 3PVU | Bovine GRK2 in complex with gbetagamma subunits and a selective kinase inhibitor (CMPD101) | x-ray diffraction | B | — | — |
| 3PVW | Bovine GRK2 in complex with Gbetagamma subunits and a selective kinase inhibitor (CMPD103A) | x-ray diffraction | B | — | — |
| 3PVW | Bovine GRK2 in complex with gbetagamma subunits and a selective kinase inhibitor (CMPD103A) | x-ray diffraction | B | — | — |
| 3UZS | Structure of the C13.28 RNA Aptamer Bound to the G Protein-Coupled Receptor Kinase 2-Heterotrimeric… | x-ray diffraction | B | — | — |
| 3UZS | Structure of the C13.28 RNA aptamer bound to the G protein-coupled receptor kinase 2-heterotrimeric… | x-ray diffraction | B | — | — |
| 3V5W | Human G Protein-Coupled Receptor Kinase 2 in Complex with Soluble Gbetagamma Subunits and Paroxetine | x-ray diffraction | B | — | — |
| 3V5W | Human G protein-coupled receptor kinase 2 in complex with soluble gbetagamma subunits and paroxetine | x-ray diffraction | B | — | — |
| 4MK0 | Crystal structure of G protein-coupled receptor kinase 2 in complex with a a rationally designed… | x-ray diffraction | B | — | — |
| 4MK0 | Crystal structure of G protein-coupled receptor kinase 2 in complex with a a rationally designed… | x-ray diffraction | B | — | — |
| 5KDO | Heterotrimeric complex of the 4 alanine insertion variant of the Gi alpha1 subunit and the… | x-ray diffraction | B | — | 6 (best 0.82) |
| 5KDO | Heterotrimeric complex of the 4 alanine insertion variant of the gi ALPHA1 subunit and the… | x-ray diffraction | B | — | — |
| 5WG3 | Human GRK2 in complex with Gbetagamma subunits and CCG258748 | x-ray diffraction | B | — | 5 (best 0.79) |
| 5WG3 | Human GRK2 in complex with gbetagamma subunits and CCG258748 | x-ray diffraction | B | — | — |
| 5WG4 | Human GRK2 in complex with Gbetagamma subunits and CCG257284 | x-ray diffraction | B | — | — |
| 5WG4 | Human GRK2 in complex with gbetagamma subunits and CCG257284 | x-ray diffraction | B | — | — |
| 5WG5 | Human GRK2 in complex with gbetagamma subunits and CCG224061 | x-ray diffraction | B | — | — |
| 6B20 | Crystal structure of a complex between G protein beta gamma dimer and an inhibitory Nanobody… | x-ray diffraction | A, B | UNX | 8 (best 0.82) |
| 6B20 | Crystal structure of a complex between G protein beta gamma dimer and an inhibitory nanobody… | x-ray diffraction | A, B | UNX | — |
| 6C2Y | Human GRK2 in complex with Gbetagamma subunits and CCG257142 | x-ray diffraction | B | — | — |
| 6C2Y | Human GRK2 in complex with gbetagamma subunits and CCG257142 | x-ray diffraction | B | — | — |
| 6OY9 | Structure of the Rhodopsin-Transducin Complex | electron microscopy | B | — | — |
| 6OY9 | Structure of the rhodopsin-transducin complex | electron microscopy | B | — | — |
| 6OYA | Structure of the Rhodopsin-Transducin-Nanobody Complex | electron microscopy | B | — | 4 (best 0.83) |
| 6OYA | Structure of the rhodopsin-transducin-nanobody complex | electron microscopy | B | — | — |
| 6PCV | Single Particle Reconstruction of Phosphatidylinositol (3,4,5) trisphosphate-dependent Rac… | electron microscopy | B | — | — |
| 6PCV | Single particle reconstruction of phosphatidylinositol (3,4,5) trisphosphate-dependent rac… | electron microscopy | B | — | — |
| 6QNO | Rhodopsin-gi protein complex | electron microscopy | B | — | — |
| 6U7C | Human GRK2 in complex with gbetagamma subunits and CCG258747 | x-ray diffraction | B | — | — |
| 7BZ2 | Cryo-EM structure of the formoterol-bound BETA2 adrenergic receptor-gs protein complex. | electron microscopy | B | — | — |
| 7D68 | Cryo-EM structure of the human glucagon-like peptide-2 receptor-gs protein complex | electron microscopy | B | — | — |
| 7DHI | Cryo-EM structure of the partial agonist salbutamol-bound beta2 adrenergic receptor-Gs protein… | electron microscopy | B | — | 5 (best 0.82) |
43 records more on the page itself.
Ligands
- UNX · Unknown atom or ion · in 2 records
Experiment against prediction
- 7TD4 chain B against the predicted model P62871: TM-score 1.00, RMSD 0.42 Å
- 7TD4 chain B against the predicted model P62871: TM-score 1.00, RMSD 0.42 Å
- 3KRW chain B against the predicted model P62871: TM-score 1.00, RMSD 0.47 Å
- 3KRW chain B against the predicted model P62871: TM-score 1.00, RMSD 0.47 Å
- 7TD3 chain B against the predicted model P62871: TM-score 0.99, RMSD 0.49 Å
- 7TD3 chain B against the predicted model P62871: TM-score 0.99, RMSD 0.49 Å
- 3KRX chain B against the predicted model P62871: TM-score 0.99, RMSD 0.48 Å
- 3KRX chain B against the predicted model P62871: TM-score 0.99, RMSD 0.48 Å
- 7PWD chain B against the predicted model P62871: TM-score 0.99, RMSD 0.49 Å
- 3CIK chain B against the predicted model P62871: TM-score 0.99, RMSD 0.50 Å
Elsewhere
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