MolNFT v1 · #185896 · protein
Torpedo muscle-type nicotinic acetylcholine receptor - resting conformation
7QKO: “Torpedo muscle-type nicotinic acetylcholine receptor - resting conformation”. Electron microscopy, 4 ligands (POV, MAN, NAG). MolNFT v1 #185896 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7QKO
- Type
- protein
- Length
- 1,996 residues
- Chains
- 5
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P02710, P02712, P02718, P02714
- Ligands
- POV, MAN, NAG, BMA
Structure
electron microscopy · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 396 | — | P02710 |
| B | — | protein | 396 | — | P02712 |
| C | — | protein | 420 | — | P02718 |
| D | — | protein | 380 | — | P02710 |
| E | — | protein | 404 | — | P02714 |
Ligands and binding sites
- POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate · ligand · 9 copies · chains A, B, E, C, D
- MAN · alpha-D-mannopyranose · sugar · 19 copies · chains A, B, C, D, E
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 14 copies · chains A, B, C, D, E
- BMA · beta-D-mannopyranose · sugar · 7 copies · chains A, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7QKO · Torpedo muscle-type nicotinic acetylcholine receptor - Resting conformation · the same entry in another collection · chain E against E, TM-score 1.00
- P02714 · AlphaFold monomer V2.0 prediction for acetylcholine receptor subunit gamma (P02714) · a predicted model of the same protein · chain E against A, TM-score 0.99
- P02712 · AlphaFold monomer V2.0 prediction for acetylcholine receptor subunit beta (P02712) · a predicted model of the same protein · chain B against A, TM-score 0.99
- P02718 · AlphaFold monomer V2.0 prediction for acetylcholine receptor subunit delta (P02718) · a predicted model of the same protein · chain C against A, TM-score 0.98
- P02710 · AlphaFold monomer V2.0 prediction for acetylcholine receptor subunit alpha (P02710) · a predicted model of the same protein · chain D against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P02710
- Every structure of UniProt P02712
- Every structure of UniProt P02718
- Every structure of UniProt P02714
- Elsewhere: RCSB PDB 7QKO · PDBe 7QKO · UniProt P02710 · UniProt P02712 · UniProt P02718 · UniProt P02714
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