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MolNFT v1 · #181955 · protein

Human cholecystokinin 1 receptor (CCK1R) gs complex

7MBX: “Human cholecystokinin 1 receptor (CCK1R) gs complex”. Electron microscopy, 2 ligands (Y01, NH2). MolNFT v1 #181955 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7MBX
Type
protein
Length
1,065 residues
Chains
6
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P63092, P54311, P59768, P06307, P32238
Ligands
Y01, NH2

Structure

electron microscopy · 6 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein240—P63092
B—protein339—P54311
G—protein58—P59768
N—protein128——
P—protein8—P06307
R—protein292—P32238

Ligands and binding sites

  • Y01 · Cholesterol hemisuccinate · ligand · chains R
  • NH2 · Amino group · ion · chains P, R

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7MBX · Human Cholecystokinin 1 receptor (CCK1R) Gs complex · the same entry in another collection · chain R against R, TM-score 1.00
  • P54311 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 1.00
  • P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.95
  • P32238 · AlphaFold monomer V2.0 prediction for cholecystokinin receptor type a (P32238) · a predicted model of the same protein · chain R against A, TM-score 0.94
  • P06307 · AlphaFold monomer V2.0 prediction for cholecystokinin (P06307) · a predicted model of the same protein · chain P against A, TM-score 0.36

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