MolNFT v1 · #180504 · protein
Orexin receptor 2 (OX2R) in complex with G protein and natural peptide-agonist orexin B (oxb)
7L1U: “Orexin receptor 2 (OX2R) in complex with G protein and natural peptide-agonist orexin B (oxb)”. Electron microscopy, 1 ligand (NH2). MolNFT v1 #180504 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7L1U
- Type
- protein
- Length
- 1,148 residues
- Chains
- 6
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P62873, P59768, Q548Y0, O43612
- Ligands
- NH2
Structure
electron microscopy · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 228 | — | — |
| B | — | protein | 339 | — | P62873 |
| C | — | protein | 58 | — | P59768 |
| H | — | protein | 233 | — | — |
| R | — | protein | 281 | — | Q548Y0 |
| L | — | protein | 9 | — | O43612 |
Ligands and binding sites
- NH2 · Amino group · ion · chains R, L
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7L1U · Orexin Receptor 2 (OX2R) in Complex with G Protein and Natural Peptide-Agonist Orexin B… · the same entry in another collection · chain L against L, TM-score 1.00
- P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
- P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain C against A, TM-score 0.94
- O43612 · AlphaFold monomer V2.0 prediction for orexin (O43612) · a predicted model of the same protein · chain L against A, TM-score 0.37
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62873
- Every structure of UniProt P59768
- Every structure of UniProt Q548Y0
- Every structure of UniProt O43612
- Elsewhere: RCSB PDB 7L1U · PDBe 7L1U · UniProt P62873 · UniProt P59768 · UniProt Q548Y0 · UniProt O43612
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