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MolNFT v1 · #179732 · protein + DNA + RNA

RNA polymerase II elongation complex with unnatural base DTPT3, rnamtp bound to E-site

7KEE: “RNA polymerase II elongation complex with unnatural base DTPT3, rnamtp bound to E-site”. X-ray diffraction, 3 ligands (WCG, ZN, MG). MolNFT v1 #179732 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7KEE
Type
protein + DNA + RNA
Length
3,582 residues
Chains
13
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P04050, P08518, P16370, P20434, P20435, P20436, P27999, P22139, P38902, P40422
Ligands
WCG, ZN, MG

Structure

x-ray diffraction · 13 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein1390—P04050
B—protein1106—P08518
C—protein266—P16370
E—protein214—P20434
F—protein84—P20435
H—protein133—P20436
I—protein119—P27999
J—protein65—P22139
K—protein114—P38902
L—protein46—P40422
R—rna10——
T—dna24——
N—dna11——

Ligands and binding sites

  • WCG · (1S)-1,4-anhydro-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-1-(3-methoxynaphthalen-2-yl)-D-ribitol · ligand · chains A, B
  • ZN · Zinc ion · metal · 8 copies · chains A, B, C, I, J, L
  • MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7KEE · RNA polymerase II elongation complex with unnatural base dTPT3, rNaMTP bound to E-site · the same entry in another collection · chain A against A, TM-score 1.00

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