MolNFT v1 · #179281 · protein
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/SSSPTA/ORMDL3, myriocin-bound
7K0Q: “Human serine palmitoyltransferase complex SPTLC1/SPLTC2/SSSPTA/ORMDL3, myriocin-bound”. Electron microscopy, 2 ligands (PLP, VRP). MolNFT v1 #179281 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7K0Q
- Type
- protein
- Length
- 1,107 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O15269, O15270, Q969W0, Q8N138
- Ligands
- PLP, VRP
Structure
electron microscopy · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 423 | — | O15269 |
| B | — | protein | 492 | — | O15270 |
| C | — | protein | 49 | — | Q969W0 |
| D | — | protein | 143 | — | Q8N138 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7K0Q · Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, myriocin-bound · the same entry in another collection · chain D against D, TM-score 1.00
- Q8N138 · AlphaFold monomer V2.0 prediction for ORM1-like protein 3 (Q8N138) · a predicted model of the same protein · chain D against A, TM-score 0.97
- O15270 · AlphaFold monomer V2.0 prediction for serine palmitoyltransferase 2 (O15270) · a predicted model of the same protein · chain B against A, TM-score 0.97
- O15269 · AlphaFold monomer V2.0 prediction for serine palmitoyltransferase 1 (O15269) · a predicted model of the same protein · chain A against A, TM-score 0.97
- Q969W0 · AlphaFold monomer V2.0 prediction for serine palmitoyltransferase small subunit a (Q969W0) · a predicted model of the same protein · chain C against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O15269
- Every structure of UniProt O15270
- Every structure of UniProt Q969W0
- Every structure of UniProt Q8N138
- Elsewhere: RCSB PDB 7K0Q · PDBe 7K0Q · UniProt O15269 · UniProt O15270 · UniProt Q969W0 · UniProt Q8N138
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