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UniProt Q8N138

ORM1-like protein 3 (Q8N138)

ORM1-like protein 3 (UniProt Q8N138): 15 experimental structures on GenesisL1, 2 ligands bound, 35 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q8N138
Protein
ORM1-like protein 3
Experimental structures
15
Predicted models
0
Ligands
2
Pockets
35 · 4 records with a druggable one

Structures

15 records of Q8N138 in the MolNFT archive: 15 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6M4NCryo-EM structure of the dimeric SPT-ORMDL3 complexelectron microscopyC, G—7 (best 0.88)
6M4NCryo-EM structure of the dimeric spt-ORMDL3 complexelectron microscopyC, G——
6M4OCryo-EM structure of the monomeric spt-ORMDL3 complexelectron microscopyA——
7CQICryo-EM structure of the substrate-bound spt-ORMDL3 complexelectron microscopyAGE0—
7CQKCryo-EM structure of the substrate-bound spt-ORMDL3 complexelectron microscopyAGE0—
7K0MHuman serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 1electron microscopyD, HPOV—
7K0MHuman serine palmitoyltransferase complex SPTLC1/SPLTC2/SSSPTA/ORMDL3, class 1electron microscopyD, HPOV—
7K0NHuman serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 2electron microscopyD, HPOV12 (best 0.89)
7K0NHuman serine palmitoyltransferase complex SPTLC1/SPLTC2/SSSPTA/ORMDL3, class 2electron microscopyD, HPOV—
7K0OHuman serine palmitoyltransferase complex SPTLC1/SPLTC2/SSSPTA/ORMDL3, class 3electron microscopyD, HPOV—
7K0PHuman serine palmitoyltransferase complex SPTLC1/SPLTC2/SSSPTA/ORMDL3, class 4electron microscopyD, HPOV—
7K0QHuman serine palmitoyltransferase complex SPTLC1/SPLTC2/SSSPTA/ORMDL3, myriocin-boundelectron microscopyD——
7YJ1Cryo-EM structure of SPT-ORMDL3 (ORMDL3-deltaN2) complexelectron microscopyD—7 (best 0.88)
7YJ2Cryo-EM structure of SPT-ORMDL3 (ORMDL3-N13A) complexelectron microscopyD—9 (best 0.84)
Q8N138AlphaFold monomer V2.0 prediction for ORM1-like protein 3 (Q8N138)———

Ligands

  • POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate · in 6 records
  • GE0 · [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3R)-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-[2-(2-oxidanylideneheptadecylsulfanyl) ethylamino]propyl]amino]butyl] hydrogen phosphate · in 2 records

Elsewhere

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