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Ligand · VRP

VRP · Myriocin

VRP, Myriocin (C21 H39 N O6, 401.5 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
VRP
Formula
C21 H39 N O6
Class
ligand
Structures
3
PDB entries
2

Binding sites

VRP in 3 structures; the first of them:

  • 7K0Q · Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, myriocin-bound · VRP B602 · binds PRO135, GLY137, PHE138, CYS336, PHE337, SER338, ALA339, TYR78 and 17 more
  • 7K0L · Human serine palmitoyltransferase complex SPTLC1/SPLTC2/SSSPTA, myriocin-bound · VRP B602 · binds PRO135, PHE138, CYS336, PHE337, SER338, TYR78, TYR122, TYR127 and 11 more
  • 7K0Q · Human serine palmitoyltransferase complex SPTLC1/SPLTC2/SSSPTA/ORMDL3, myriocin-bound · VRP B602 · binds PRO135, PHE138, CYS336, PHE337, TYR78, TYR122, LEU126, TYR127 and 11 more

Residues it binds most

TYR 3, PHE 3, PRO 3, HIS 3, SER 3, GLY 3, ILE 3, ARG 3, CYS 3, LYS 3 (residue and the binding sites it lines).

Found with

  • PLP · Pyridoxal-5'-phosphate

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