MolNFT v1 · #178158 · protein
Cryo-EM structure of human bradykinin receptor BK2R in complex gq proteins and bradykinin
7F6H: “Cryo-EM structure of human bradykinin receptor BK2R in complex gq proteins and bradykinin”. Electron microscopy, 1 ligand (CLR). MolNFT v1 #178158 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7F6H
- Type
- protein
- Length
- 917 residues
- Chains
- 5
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P50148, P62873, P59768
- Ligands
- CLR
Structure
electron microscopy · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 305 | — | — |
| L | — | protein | 9 | — | — |
| B | — | protein | 226 | — | P50148 |
| C | — | protein | 330 | — | P62873 |
| D | — | protein | 47 | — | P59768 |
Ligands and binding sites
- CLR · Cholesterol · ligand · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7F6H · Cryo-EM structure of human bradykinin receptor BK2R in complex Gq proteins and bradykinin · the same entry in another collection · chain D against D, TM-score 1.00
- P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain C against A, TM-score 0.99
- P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain D against A, TM-score 0.92
- P50148 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(Q) subunit… · a predicted model of the same protein · chain B against A, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P50148
- Every structure of UniProt P62873
- Every structure of UniProt P59768
- Elsewhere: RCSB PDB 7F6H · PDBe 7F6H · UniProt P50148 · UniProt P62873 · UniProt P59768
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