MolNFT v1 · #178124 · protein
Lbd-tmd focused reconstruction of dnqx-bound GLUK2-1XNETO2 complex
7F5B: “Lbd-tmd focused reconstruction of dnqx-bound GLUK2-1XNETO2 complex”. Electron microscopy, 4 ligands (PGT, NAG, BMA). MolNFT v1 #178124 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7F5B
- Type
- protein
- Length
- 1,921 residues
- Chains
- 5
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P42260, C6K2K4
- Ligands
- PGT, NAG, BMA, CA
Structure
electron microscopy · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C | — | protein | 437 | — | P42260 |
| B | — | protein | 433 | — | P42260 |
| D | — | protein | 420 | — | P42260 |
| E | — | protein | 194 | — | C6K2K4 |
Ligands and binding sites
- PGT · (1S)-2-{[{[(2R)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate · ligand · chains C, D
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 10 copies · chains B, D, A, C
- BMA · beta-D-mannopyranose · sugar · 2 copies · chains D
- CA · Calcium ion · metal · chains A, B, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7F5B · LBD-TMD focused reconstruction of DNQX-bound GluK2-1xNeto2 complex · the same entry in another collection · chain E against E, TM-score 1.00
- C6K2K4 · AlphaFold monomer V2.0 prediction for neuropilin and tolloid-like protein 2 (C6K2K4) · a predicted model of the same protein · chain E against A, TM-score 0.74
- P42260 · AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, kainate 2 (P42260) · a predicted model of the same protein · chain D against A, TM-score 0.70
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P42260
- Every structure of UniProt C6K2K4
- Elsewhere: RCSB PDB 7F5B · PDBe 7F5B · UniProt P42260 · UniProt C6K2K4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.