UniProt C6K2K4
Neuropilin and tolloid-like protein 2 (C6K2K4)
Neuropilin and tolloid-like protein 2 (UniProt C6K2K4): 9 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- C6K2K4
- Protein
- Neuropilin and tolloid-like protein 2
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 11 · 5 records with a druggable one
Structures
10 records of C6K2K4 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7F56 | DNQX-bound GluK2-1xNeto2 complex, with asymmetric LBD | electron microscopy | E | BMA | 1 (best 0.74) |
| 7F56 | Dnqx-bound GLUK2-1XNETO2 complex, with asymmetric lbd | electron microscopy | E | BMA | — |
| 7F57 | Kainate-bound GLUK2-1XNETO2 complex, at the desensitized state | electron microscopy | E | NAG, BMA | — |
| 7F59 | DNQX-bound GluK2-1xNeto2 complex | electron microscopy | E | BMA | 2 (best 0.74) |
| 7F59 | Dnqx-bound GLUK2-1XNETO2 complex | electron microscopy | E | — | — |
| 7F5A | DNQX-bound GluK2-2xNeto2 complex | electron microscopy | E, F | — | 3 (best 0.77) |
| 7F5A | Dnqx-bound GLUK2-2XNETO2 complex | electron microscopy | E, F | — | — |
| 7F5B | LBD-TMD focused reconstruction of DNQX-bound GluK2-1xNeto2 complex | electron microscopy | E | PGT | 3 (best 0.55) |
| 7F5B | Lbd-tmd focused reconstruction of dnqx-bound GLUK2-1XNETO2 complex | electron microscopy | E | — | — |
| C6K2K4 | AlphaFold monomer V2.0 prediction for neuropilin and tolloid-like protein 2 (C6K2K4) | predicted | A | — | 2 (best 0.55) |
Ligands
Experiment against prediction
- 7F5B chain E against the predicted model C6K2K4: TM-score 0.74, RMSD 1.79 Å
- 7F5B chain E against the predicted model C6K2K4: TM-score 0.74, RMSD 1.79 Å
- 7F57 chain E against the predicted model C6K2K4: TM-score 0.68, RMSD 2.28 Å
- 7F56 chain E against the predicted model C6K2K4: TM-score 0.68, RMSD 3.24 Å
- 7F56 chain E against the predicted model C6K2K4: TM-score 0.68, RMSD 3.24 Å
- 7F5A chain E against the predicted model C6K2K4: TM-score 0.68, RMSD 3.54 Å
- 7F5A chain E against the predicted model C6K2K4: TM-score 0.68, RMSD 3.54 Å
- 7F5A chain F against the predicted model C6K2K4: TM-score 0.56, RMSD 4.46 Å
- 7F5A chain F against the predicted model C6K2K4: TM-score 0.56, RMSD 4.46 Å
- 7F59 chain E against the predicted model C6K2K4: TM-score 0.55, RMSD 4.75 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.