MolNFT v1 · #178117 · protein
Cryo-EM structure of afamelanotide-MC4R-GS_NB35 complex
7F54: “Cryo-EM structure of afamelanotide-MC4R-GS_NB35 complex”. Electron microscopy, 1 ligand (CA). MolNFT v1 #178117 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7F54
- Type
- protein
- Length
- 1,034 residues
- Chains
- 6
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P62873, P59768, P32245
- Ligands
- CA
Structure
electron microscopy · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 227 | — | — |
| B | — | protein | 338 | — | P62873 |
| G | — | protein | 57 | — | P59768 |
| N | — | protein | 126 | — | — |
| R | — | protein | 273 | — | P32245 |
| L | — | protein | 13 | — | — |
Ligands and binding sites
- CA · Calcium ion · metal · chains R, L
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7F54 · Cryo-EM structure of afamelanotide-MC4R-Gs_Nb35 complex · the same entry in another collection · chain L against L, TM-score 1.00
- P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 1.00
- P32245 · AlphaFold monomer V2.0 prediction for melanocortin receptor 4 (P32245) · a predicted model of the same protein · chain R against A, TM-score 0.95
- P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62873
- Every structure of UniProt P59768
- Every structure of UniProt P32245
- Elsewhere: RCSB PDB 7F54 · PDBe 7F54 · UniProt P62873 · UniProt P59768 · UniProt P32245
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