MolNFT v1 · #176294 · protein
Cryo-EM structure of the full agonist isoprenaline-bound BETA2 adrenergic receptor-gs protein complex.
7DHR: “Cryo-EM structure of the full agonist isoprenaline-bound BETA2 adrenergic receptor-gs protein complex.”. Electron microscopy, 1 ligand (5FW). MolNFT v1 #176294 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7DHR
- Type
- protein
- Length
- 977 residues
- Chains
- 5
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P63092, P62871, P63212, P07550
- Ligands
- 5FW
Structure
electron microscopy · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 194 | — | P63092 |
| B | — | protein | 327 | — | P62871 |
| G | — | protein | 49 | — | P63212 |
| N | — | protein | 123 | — | — |
| R | — | protein | 284 | — | P07550 |
Ligands and binding sites
- 5FW · Isoprenaline · ligand · chains R
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7DHR · Cryo-EM structure of the full agonist isoprenaline-bound beta2 adrenergic receptor-Gs… · the same entry in another collection · chain R against R, TM-score 1.00
- P62871 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
- P07550 · AlphaFold monomer V2.0 prediction for beta-2 adrenergic receptor (P07550) · a predicted model of the same protein · chain R against A, TM-score 0.92
- P63212 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.60
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63092
- Every structure of UniProt P62871
- Every structure of UniProt P63212
- Every structure of UniProt P07550
- Elsewhere: RCSB PDB 7DHR · PDBe 7DHR · UniProt P63092 · UniProt P62871 · UniProt P63212 · UniProt P07550
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