MolNFT v1 · #173019 · protein

Crystal structure of TD1-GATORBULIN1 complex

7ALR: “Crystal structure of TD1-GATORBULIN1 complex”. X-ray diffraction, 5 ligands (GTP, RQK, GDP). MolNFT v1 #173019 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7ALR
Type: protein
Length: 1,009 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P81947, Q2T9S0
Ligands: GTP, RQK, GDP, MG, SO4

Structure

x-ray diffraction · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	426	—	P81947
B	—	protein	428	—	Q2T9S0
F	—	protein	155	—	—

Ligands and binding sites

GTP · Guanosine-5'-triphosphate · ligand · chains A, B
RQK · (2~{R})-2-oxidanyl-2-[(6~{S},9~{S},12~{S},15~{S}, 17~{S})-6,10,12,17-tetramethyl-3-methylidene-7-oxidanyl-2,5,8,11,14-pentakis(oxidanylidene)-13-oxa-1, 4,7,10-tetrazabicyclo[13.3.0]octadecan-9-yl]ethanamide · ligand · chains A, B
GDP · Guanosine-5'-diphosphate · ligand · chains B
MG · Magnesium ion · metal · chains A, B
SO4 · Sulfate ion · ion · 2 copies · chains A, B
GOL · Glycerol · additive · 3 copies · chains B, F

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7ALR · Crystal structure of TD1-gatorbulin1 complex · the same entry in another collection · chain B against B, TM-score 1.00
Q2T9S0 · AlphaFold monomer V2.0 prediction for tubulin beta-3 chain (Q2T9S0) · a predicted model of the same protein · chain B against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P81947
Every structure of UniProt Q2T9S0
Elsewhere: RCSB PDB 7ALR · PDBe 7ALR · UniProt P81947 · UniProt Q2T9S0

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