GL1X · GenesisL1 explorer

MolNFT v1 · #168514 · protein

Structure of human GABA(B) receptor in an inactive state

6WIV: “Structure of human GABA(B) receptor in an inactive state”. Electron microscopy, 5 ligands (CLR, U3G, U3D). MolNFT v1 #168514 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6WIV
Type
protein
Length
1,352 residues
Chains
2
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q9UBS5, O75899
Ligands
CLR, U3G, U3D, NAG, CA

Structure

electron microscopy · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein681—Q9UBS5
B—protein671—O75899

Ligands and binding sites

  • CLR · Cholesterol · ligand · 10 copies · chains A, B
  • U3G · (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-{[(9Z)-octadec-9-enoyl]oxy}propyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate · ligand · chains A
  • U3D · [(2R)-3-[(Z)-icos-11-enoyl]oxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate · ligand · chains B
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains A, B
  • CA · Calcium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6WIV · Structure of human GABA(B) receptor in an inactive state · the same entry in another collection · chain A against A, TM-score 1.00
  • O75899 · AlphaFold monomer V2.0 prediction for gamma-aminobutyric acid type B receptor subunit 2… · a predicted model of the same protein · chain B against A, TM-score 0.95
  • Q9UBS5 · AlphaFold monomer V2.0 prediction for gamma-aminobutyric acid type B receptor subunit 1… · a predicted model of the same protein · chain A against A, TM-score 0.85

Analyse

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.