MolNFT v1 · #149673 · protein
Coupling specificity of heterotrimeric go to the serotonin 5-HT1B receptor
6G79: “Coupling specificity of heterotrimeric go to the serotonin 5-HT1B receptor”. Electron microscopy, 1 ligand (EP5). MolNFT v1 #149673 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6G79
- Type
- protein
- Length
- 860 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P62873, P59768, P09471, A0A0P7W0C8, P28222
- Ligands
- EP5
Structure
electron microscopy · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | — | protein | 333 | — | P62873 |
| G | — | protein | 56 | — | P59768 |
| A | — | protein | 209 | — | P09471, A0A0P7W0C8 |
| S | — | protein | 262 | — | P28222 |
Ligands and binding sites
- EP5 · 2-[5-[2-[4-(4-cyanophenyl)piperazin-1-yl]-2-oxidanylidene-ethoxy]-1~{H}-indol-3-yl]ethylazanium · ligand · chains S
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6G79 · Coupling specificity of heterotrimeric Go to the serotonin 5-HT1B receptor · the same entry in another collection · chain S against S, TM-score 1.00
- P62873 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(T)… · a predicted model of the same protein · chain B against A, TM-score 0.99
- P59768 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(I)/G(S)/G(O)… · a predicted model of the same protein · chain G against A, TM-score 0.95
- P28222 · AlphaFold monomer V2.0 prediction for 5-hydroxytryptamine receptor 1B (P28222) · a predicted model of the same protein · chain S against A, TM-score 0.94
- P09471 · AlphaFold monomer V2.0 prediction for guanine nucleotide-binding protein G(O) subunit… · a predicted model of the same protein · chain A against A, TM-score 0.77
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P62873
- Every structure of UniProt P59768
- Every structure of UniProt P09471
- Every structure of UniProt A0A0P7W0C8
- Every structure of UniProt P28222
- Elsewhere: RCSB PDB 6G79 · PDBe 6G79 · UniProt P62873 · UniProt P59768 · UniProt P09471 · UniProt A0A0P7W0C8 · UniProt P28222
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