MolNFT v1 · #125080 · protein

Mouse POFUT1 in complex with O-glucosylated mouse NOTCH1 EGF12 mutant (D464G) and GDP

5KY8: “Mouse POFUT1 in complex with O-glucosylated mouse NOTCH1 EGF12 mutant (D464G) and GDP”. X-ray diffraction, 3 ligands (GDP, NAG, BGC). MolNFT v1 #125080 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5KY8
Type: protein
Length: 391 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q91ZW2, Q01705
Ligands: GDP, NAG, BGC

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	352	—	Q91ZW2
B	—	protein	39	—	Q01705

Ligands and binding sites

GDP · Guanosine-5'-diphosphate · ligand · chains A
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
BGC · beta-D-glucopyranose · sugar · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5KY8 · mouse POFUT1 in complex with O-glucosylated mouse Notch1 EGF12 mutant (D464G) and GDP · the same entry in another collection · chain A against A, TM-score 1.00
Q91ZW2 · AlphaFold monomer V2.0 prediction for GDP-fucose protein O-fucosyltransferase 1 (Q91ZW2) · a predicted model of the same protein · chain A against A, TM-score 0.99
Q01705 · AlphaFold monomer V2.0 prediction for neurogenic locus notch homolog protein 1 (Q01705) · a predicted model of the same protein · chain B against A, TM-score 0.81

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q91ZW2
Every structure of UniProt Q01705
Elsewhere: RCSB PDB 5KY8 · PDBe 5KY8 · UniProt Q91ZW2 · UniProt Q01705

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