Single chain recombinant globular head of the complement system protein C1Q

Structure

x-ray diffraction · 1 distinct chain · 1% helix, 55% strand (DSSP).

Ligands and binding sites

• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
• CA · Calcium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

• 5HKJ · Single Chain Recombinant Globular Head of the Complement System Protein C1q · the same entry in another collection · chain A against A, TM-score 1.00
• P02746 · AlphaFold monomer V2.0 prediction for complement C1Q subcomponent subunit B (P02746) · a predicted model of the same protein · chain A against A, TM-score 0.38
• P02747 · AlphaFold monomer V2.0 prediction for complement C1Q subcomponent subunit C (P02747) · a predicted model of the same protein · chain A against A, TM-score 0.34
• P02745 · AlphaFold monomer V2.0 prediction for complement C1Q subcomponent subunit a (P02745) · a predicted model of the same protein · chain A against A, TM-score 0.33

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P02745
• Every structure of UniProt P02747
• Every structure of UniProt P02746
• Elsewhere: RCSB PDB 5HKJ · PDBe 5HKJ · UniProt P02745 · UniProt P02747 · UniProt P02746