UniProt P02746
Complement C1q subcomponent subunit B (P02746)
Complement C1q subcomponent subunit B (UniProt P02746): 18 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02746
- Protein
- Complement C1q subcomponent subunit B
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 16 · 4 records with a druggable one
Structures
19 records of P02746 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PK6 | Globular Head of the Complement System Protein C1q | x-ray diffraction | B | — | — |
| 1PK6 | Globular head of the complement system protein C1Q | x-ray diffraction | B | — | — |
| 2JG8 | Crystallographic structure of human C1q globular heads complexed to phosphatidyl-serine | x-ray diffraction | B, E | — | — |
| 2JG8 | Crystallographic structure of human C1Q globular heads complexed to phosphatidyl-serine | x-ray diffraction | B, E | — | — |
| 2JG9 | Crystallographic structure of human C1q globular heads (P1) | x-ray diffraction | B, E | — | — |
| 2JG9 | Crystallographic structure of human C1Q globular heads (P1) | x-ray diffraction | B, E | — | — |
| 2WNU | Complex between c1q globular heads and heparan sulfate | x-ray diffraction | B, E | — | — |
| 2WNU | Complex between C1Q globular heads and heparan sulfate | x-ray diffraction | B, E | — | — |
| 2WNV | Complex between C1q globular heads and deoxyribose | x-ray diffraction | B, E | — | — |
| 2WNV | Complex between C1Q globular heads and deoxyribose | x-ray diffraction | B, E | — | — |
| 5HKJ | Single Chain Recombinant Globular Head of the Complement System Protein C1q | x-ray diffraction | A | NAG, CA | 2 (best 0.63) |
| 5HKJ | Single chain recombinant globular head of the complement system protein C1Q | x-ray diffraction | A | — | — |
| 5HZF | Single Chain Recombinant Globular Head of the Complement System Protein C1q in complex with… | x-ray diffraction | A | MG | 3 (best 0.60) |
| 5HZF | Single chain recombinant globular head of the complement system protein C1Q in complex with… | x-ray diffraction | A | — | — |
| 6FCZ | Model of gC1q-Fc complex based on 7A EM map | electron microscopy | B | — | 6 (best 0.51) |
| 6FCZ | Model of GC1Q-Fc complex based on 7A EM MAP | electron microscopy | B | — | — |
| 6Z6V | Globular head of C1q in complex with the nanobody C1qNb75 | x-ray diffraction | B, E | — | 5 (best 0.64) |
| 6Z6V | Globular head of C1Q in complex with the nanobody C1QNB75 | x-ray diffraction | B, E | — | — |
| P02746 | AlphaFold monomer V2.0 prediction for complement C1Q subcomponent subunit B (P02746) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2JG8 chain E against the predicted model P02746: TM-score 1.00, RMSD 0.29 Å
- 2JG8 chain E against the predicted model P02746: TM-score 1.00, RMSD 0.29 Å
- 2WNV chain B against the predicted model P02746: TM-score 0.99, RMSD 0.37 Å
- 2WNV chain B against the predicted model P02746: TM-score 0.99, RMSD 0.37 Å
- 2JG9 chain E against the predicted model P02746: TM-score 0.99, RMSD 0.37 Å
- 2JG9 chain E against the predicted model P02746: TM-score 0.99, RMSD 0.37 Å
- 2JG9 chain B against the predicted model P02746: TM-score 0.99, RMSD 0.37 Å
- 2JG9 chain B against the predicted model P02746: TM-score 0.99, RMSD 0.37 Å
- 2JG8 chain B against the predicted model P02746: TM-score 0.99, RMSD 0.41 Å
- 2JG8 chain B against the predicted model P02746: TM-score 0.99, RMSD 0.41 Å
Elsewhere
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