UniProt P02745
Complement C1q subcomponent subunit A (P02745)
Complement C1q subcomponent subunit A (UniProt P02745): 18 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P02745
- Protein
- Complement C1q subcomponent subunit A
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 10 · 3 records with a druggable one
Structures
19 records of P02745 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PK6 | Globular Head of the Complement System Protein C1q | x-ray diffraction | A | — | — |
| 1PK6 | Globular head of the complement system protein C1Q | x-ray diffraction | A | — | — |
| 2JG8 | Crystallographic structure of human C1q globular heads complexed to phosphatidyl-serine | x-ray diffraction | A, D | — | — |
| 2JG8 | Crystallographic structure of human C1Q globular heads complexed to phosphatidyl-serine | x-ray diffraction | A, D | — | — |
| 2JG9 | Crystallographic structure of human C1q globular heads (P1) | x-ray diffraction | A, D | — | — |
| 2JG9 | Crystallographic structure of human C1Q globular heads (P1) | x-ray diffraction | A, D | — | — |
| 2WNU | Complex between c1q globular heads and heparan sulfate | x-ray diffraction | A, D | — | — |
| 2WNU | Complex between C1Q globular heads and heparan sulfate | x-ray diffraction | A, D | — | — |
| 2WNV | Complex between C1q globular heads and deoxyribose | x-ray diffraction | A, D | — | — |
| 2WNV | Complex between C1Q globular heads and deoxyribose | x-ray diffraction | A, D | — | — |
| 5HKJ | Single Chain Recombinant Globular Head of the Complement System Protein C1q | x-ray diffraction | A | NAG, CA | 2 (best 0.63) |
| 5HKJ | Single chain recombinant globular head of the complement system protein C1Q | x-ray diffraction | A | — | — |
| 5HZF | Single Chain Recombinant Globular Head of the Complement System Protein C1q in complex with… | x-ray diffraction | A | MG | 3 (best 0.60) |
| 5HZF | Single chain recombinant globular head of the complement system protein C1Q in complex with… | x-ray diffraction | A | — | — |
| 6FCZ | Model of gC1q-Fc complex based on 7A EM map | electron microscopy | A | — | 3 (best 0.44) |
| 6FCZ | Model of GC1Q-Fc complex based on 7A EM MAP | electron microscopy | A | — | — |
| 6Z6V | Globular head of C1q in complex with the nanobody C1qNb75 | x-ray diffraction | A, D | NAG | 2 (best 0.64) |
| 6Z6V | Globular head of C1Q in complex with the nanobody C1QNB75 | x-ray diffraction | A, D | NAG | — |
| P02745 | AlphaFold monomer V2.0 prediction for complement C1Q subcomponent subunit a (P02745) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1PK6 chain A against the predicted model P02745: TM-score 0.99, RMSD 0.51 Å
- 1PK6 chain A against the predicted model P02745: TM-score 0.99, RMSD 0.51 Å
- 6FCZ chain A against the predicted model P02745: TM-score 0.99, RMSD 0.51 Å
- 6FCZ chain A against the predicted model P02745: TM-score 0.99, RMSD 0.51 Å
- 2JG9 chain A against the predicted model P02745: TM-score 0.99, RMSD 0.54 Å
- 2JG9 chain A against the predicted model P02745: TM-score 0.99, RMSD 0.54 Å
- 2JG9 chain D against the predicted model P02745: TM-score 0.99, RMSD 0.54 Å
- 2JG9 chain D against the predicted model P02745: TM-score 0.99, RMSD 0.54 Å
- 2WNU chain A against the predicted model P02745: TM-score 0.99, RMSD 0.54 Å
- 2WNU chain A against the predicted model P02745: TM-score 0.99, RMSD 0.54 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.