MolNFT v1 · #432074 · protein
AlphaFold monomer V2.0 prediction for sorting nexin-5 (Q9Y5X3)
Q9Y5X3: “AlphaFold monomer V2.0 prediction for sorting nexin-5 (Q9Y5X3)”. 4 pockets (best druggability 0.73). MolNFT v1 #432074 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9Y5X3
- Type
- protein
- Length
- 404 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7c75F0f7d6d136A2b8D4C6C6e9b3D8a697949DF1
- Molecule
- Sorting nexin-5
- UniProt
- Q9Y5X3
- Pockets
- 4 · best druggability 0.73
Structure
1 distinct chain · 73% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sorting nexin-5 | protein | 404 | 73% helix, 7% strand | Q9Y5X3 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 857 | 0.73 | 0.77 | 75 | empty |
| 2 | 591 | 0.65 | 0.75 | 57 | empty |
| 3 | 127 | 0.60 | 0.85 | 24 | empty |
| 4 | 54 | 0.25 | 0.73 | 13 | empty |
Compared structures
- 8A1G · Structure of the SNX1-SNX5 complex · an experimental structure of the same protein · chain A against C, TM-score 0.45
- 5WY2 · Human SNX5 px domain in complex with chlamydia ince C terminus · an experimental structure of the same protein · chain A against C, TM-score 0.36
- 6N5Y · Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121… · an experimental structure of the same protein · chain A against A, TM-score 0.35
- 6N5Y · Crystal structure of the SNX5 px domain in complex with the ci-mpr (space group P212121… · an experimental structure of the same protein · chain A against A, TM-score 0.35
- 6N5Z · Crystal structure of the SNX5 px domain in complex with the SEMA4C · an experimental structure of the same protein · chain A against A, TM-score 0.35
- 6N5Z · Crystal structure of the SNX5 PX domain in complex with the Sema4C · an experimental structure of the same protein · chain A against A, TM-score 0.35
- 6N5X · Crystal structure of the SNX5 px domain in complex with the ci-mpr (space group P212121… · an experimental structure of the same protein · chain A against A, TM-score 0.35
- 6N5X · Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121… · an experimental structure of the same protein · chain A against A, TM-score 0.35
- 5TGJ · Structure of the SNX5 px domain in complex with chlamydial protein ince in space group I2 · an experimental structure of the same protein · chain A against A, TM-score 0.35
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y5X3
- Elsewhere: UniProt Q9Y5X3 · AlphaFold DB Q9Y5X3
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