UniProt Q9Y5X3
Sorting nexin-5 (Q9Y5X3)
Sorting nexin-5 (UniProt Q9Y5X3): 14 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y5X3
- Protein
- Sorting nexin-5
- Experimental structures
- 14
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 7 · 2 records with a druggable one
Structures
15 records of Q9Y5X3 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1SYS | Crystal structure of HLA, B*4403, and peptide EEPTVIKKY | x-ray diffraction | C | — | — |
| 1SYS | Crystal structure of HLA, B*4403, and peptide eeptvikky | x-ray diffraction | C | — | — |
| 5TGH | Structure of the SNX5 px domain in complex with chlamydial protein ince in space group P32 | x-ray diffraction | A, C, E, G | — | — |
| 5TGI | Structure of the SNX5 px domain in complex with chlamydial protein ince in space group P212121 | x-ray diffraction | A, B | — | — |
| 5TGJ | Structure of the SNX5 PX domain in complex with chlamydial protein IncE in space group I2 | x-ray diffraction | A, C | — | 3 (best 0.68) |
| 5TGJ | Structure of the SNX5 px domain in complex with chlamydial protein ince in space group I2 | x-ray diffraction | A, C | — | — |
| 5WY2 | Human SNX5 px domain in complex with chlamydia ince C terminus | x-ray diffraction | A, C | — | — |
| 6N5X | Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1) | x-ray diffraction | A | JEF | — |
| 6N5X | Crystal structure of the SNX5 px domain in complex with the ci-mpr (space group P212121 - form 1) | x-ray diffraction | A | JEF | — |
| 6N5Y | Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121 - Form 1) | x-ray diffraction | A | — | — |
| 6N5Y | Crystal structure of the SNX5 px domain in complex with the ci-mpr (space group P212121 - form 1) | x-ray diffraction | A | — | — |
| 6N5Z | Crystal structure of the SNX5 PX domain in complex with the Sema4C | x-ray diffraction | A, B | CL | — |
| 6N5Z | Crystal structure of the SNX5 px domain in complex with the SEMA4C | x-ray diffraction | A, B | CL | — |
| 8A1G | Structure of the SNX1-SNX5 complex | x-ray diffraction | C, D | — | — |
| Q9Y5X3 | AlphaFold monomer V2.0 prediction for sorting nexin-5 (Q9Y5X3) | predicted | A | — | 4 (best 0.73) |
Ligands
Experiment against prediction
- 8A1G chain C against the predicted model Q9Y5X3: TM-score 0.96, RMSD 1.06 Å
- 5WY2 chain A against the predicted model Q9Y5X3: TM-score 0.96, RMSD 0.90 Å
- 5TGJ chain A against the predicted model Q9Y5X3: TM-score 0.96, RMSD 1.09 Å
- 5TGJ chain A against the predicted model Q9Y5X3: TM-score 0.96, RMSD 1.09 Å
- 8A1G chain D against the predicted model Q9Y5X3: TM-score 0.96, RMSD 1.10 Å
- 5TGH chain A against the predicted model Q9Y5X3: TM-score 0.95, RMSD 1.19 Å
- 5TGH chain E against the predicted model Q9Y5X3: TM-score 0.94, RMSD 1.12 Å
- 5TGI chain A against the predicted model Q9Y5X3: TM-score 0.94, RMSD 1.27 Å
- 5TGJ chain C against the predicted model Q9Y5X3: TM-score 0.93, RMSD 1.26 Å
- 5TGJ chain C against the predicted model Q9Y5X3: TM-score 0.93, RMSD 1.26 Å
Elsewhere
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