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MolNFT v1 · #157643 · protein

Crystal structure of the SNX5 px domain in complex with the ci-mpr (space group P212121 - form 1)

6N5Y · Sorting nexin-5,CATION-independent mannose-6-phosphate…: “Crystal structure of the SNX5 px domain in complex with the ci-mpr (space group P212121 - form 1)”. X-ray diffraction, 1 pocket (best druggability 0.34). MolNFT v1 #157643 on…

PDB
6N5Y
Type
protein
Length
162 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Sorting nexin-5,CATION-independent mannose-6-phosphate receptor
UniProt
Q9Y5X3, P11717
Pockets
1 · best druggability 0.34

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 26% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASorting nexin-5,CATION-independent mannose-6-phosphate receptorprotein16246% helix, 26% strandQ9Y5X3, P11717

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1640.340.7714empty

Compared structures

  • 6N5Y · Crystal structure of the SNX5 PX domain in complex with the CI-MPR (space group P212121… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9Y5X3 · AlphaFold monomer V2.0 prediction for sorting nexin-5 (Q9Y5X3) · a predicted model of the same protein · chain A against A, TM-score 0.87
  • P11717 · AlphaFold monomer V2.0 prediction for cation-independent mannose-6-phosphate receptor… · a predicted model of the same protein · chain A against A, TM-score 0.35

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