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MolNFT v1 · #431921 · protein

AlphaFold monomer V2.0 prediction for U1 small nuclear ribonucleoprotein component SNU71 (P53207)

P53207: “AlphaFold monomer V2.0 prediction for U1 small nuclear ribonucleoprotein component SNU71 (P53207)”. 5 pockets (best druggability 0.59). MolNFT v1 #431921 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
P53207
Type
protein
Length
620 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xd10960F956646DE8b64d3598984c91C2d5Af3D7b
Molecule
U1 small nuclear ribonucleoprotein component SNU71
UniProt
P53207
Pockets
5 · best druggability 0.59

Structure

1 distinct chain · 50% helix, 6% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AU1 small nuclear ribonucleoprotein component SNU71protein62050% helix, 6% strandP53207

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14260.590.7533empty
22230.480.7533empty
3660.420.8116empty
4680.330.7518empty
5510.270.7415empty

Compared structures

  • 6N7P · S. cerevisiae spliceosomal E complex (UBC4) · an experimental structure of the same protein · chain A against H, TM-score 0.08
  • 6N7P · S. cerevisiae spliceosomal E complex (UBC4) · an experimental structure of the same protein · chain A against H, TM-score 0.08
  • 7OQC · The U1 part of saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) · an experimental structure of the same protein · chain A against J, TM-score 0.08
  • 7OQE · Saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) · an experimental structure of the same protein · chain A against J, TM-score 0.08
  • 6N7R · Saccharomyces cerevisiae spliceosomal E complex (ACT1) · an experimental structure of the same protein · chain A against H, TM-score 0.08
  • 8W2O · Yeast U1 snRNP with humanized U1C Zinc-Finger domain · an experimental structure of the same protein · chain A against H, TM-score 0.08
  • 6N7X · S. cerevisiae U1 snrnp · an experimental structure of the same protein · chain A against H, TM-score 0.08
  • 6N7X · S. cerevisiae U1 snRNP · an experimental structure of the same protein · chain A against H, TM-score 0.08
  • 5ZWN · Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.3 ångström… · an experimental structure of the same protein · chain A against X, TM-score 0.08
  • 5ZWN · Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.3 angstrom… · an experimental structure of the same protein · chain A against X, TM-score 0.08
  • 6G90 · Prespliceosome structure provides insight into spliceosome assembly and regulation (MAP… · an experimental structure of the same protein · chain A against J, TM-score 0.07

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