MolNFT v1 · #430859 · protein
AlphaFold monomer V2.0 prediction for structural maintenance of chromosomes protein 3 (P47037)
P47037: “AlphaFold monomer V2.0 prediction for structural maintenance of chromosomes protein 3 (P47037)”. 10 pockets (best druggability 0.51). MolNFT v1 #430859 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P47037
- Type
- protein
- Length
- 1,230 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xbb2F1C7CB3A1eeFAc24fCa72cc627162D5413FD7
- Molecule
- Structural maintenance of chromosomes protein 3
- UniProt
- P47037
- Pockets
- 10 · best druggability 0.51
Structure
1 distinct chain · 69% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Structural maintenance of chromosomes protein 3 | protein | 1230 | 69% helix, 10% strand | P47037 |
Pockets
10 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 102 | 0.51 | 0.82 | 29 | empty |
| 2 | 171 | 0.50 | 0.77 | 19 | empty |
| 3 | 55 | 0.42 | 0.83 | 14 | empty |
| 4 | 83 | 0.40 | 0.78 | 12 | empty |
| 5 | 68 | 0.39 | 0.79 | 12 | empty |
Compared structures
- 7OGT · Folded elbow of cohesin · an experimental structure of the same protein · chain A against B, TM-score 0.44
- 4UX3 · Cohesin SMC3-HD:SCC1-N complex from yeast · an experimental structure of the same protein · chain A against A, TM-score 0.31
- 4UX3 · cohesin Smc3-HD:Scc1-N complex from yeast · an experimental structure of the same protein · chain A against A, TM-score 0.31
- 6ZZ6 · Cryo-EM structure of S.CEREVISIAE cohesin-SCC2-DNA complex · an experimental structure of the same protein · chain A against B, TM-score 0.30
- 6QPW · Structural basis of cohesin ring opening · an experimental structure of the same protein · chain A against C, TM-score 0.28
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P47037
- Elsewhere: UniProt P47037 · AlphaFold DB P47037
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