UniProt P47037
Structural maintenance of chromosomes protein 3 (P47037)
Structural maintenance of chromosomes protein 3 (UniProt P47037): 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P47037
- Protein
- Structural maintenance of chromosomes protein 3
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 23 · 2 records with a druggable one
Structures
7 records of P47037 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4UX3 | cohesin Smc3-HD:Scc1-N complex from yeast | x-ray diffraction | A | — | — |
| 4UX3 | Cohesin SMC3-HD:SCC1-N complex from yeast | x-ray diffraction | A | — | — |
| 6QPW | Structural basis of cohesin ring opening | electron microscopy | C | AGS, MG | — |
| 6ZZ6 | Cryo-EM structure of S.cerevisiae cohesin-Scc2-DNA complex | electron microscopy | B | ATP, MG | 13 (best 0.80) |
| 6ZZ6 | Cryo-EM structure of S.CEREVISIAE cohesin-SCC2-DNA complex | electron microscopy | B | ATP, MG | — |
| 7OGT | Folded elbow of cohesin | electron microscopy | B | — | — |
| P47037 | AlphaFold monomer V2.0 prediction for structural maintenance of chromosomes protein 3 (P47037) | predicted | A | — | 10 (best 0.51) |
Ligands
Experiment against prediction
- 6QPW chain C against the predicted model P47037: TM-score 0.85, RMSD 3.30 Å
- 6ZZ6 chain B against the predicted model P47037: TM-score 0.83, RMSD 3.09 Å
- 6ZZ6 chain B against the predicted model P47037: TM-score 0.83, RMSD 3.09 Å
- 4UX3 chain A against the predicted model P47037: TM-score 0.79, RMSD 3.62 Å
- 4UX3 chain A against the predicted model P47037: TM-score 0.79, RMSD 3.62 Å
- 7OGT chain B against the predicted model P47037: TM-score 0.70, RMSD 6.08 Å
Elsewhere
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