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AlphaFold monomer V2.0 prediction for structural maintenance of chromosomes protein 3 (P47037)

Analyse AlphaFold monomer V2.0 prediction for structural maintenance of chromosomes… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P47037
Type
protein
Length
1,230 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xbb2F1C7CB3A1eeFAc24fCa72cc627162D5413FD7
Molecule
Structural maintenance of chromosomes protein 3
UniProt
P47037
Pockets
10 · best druggability 0.51

Structure

1 distinct chain · 69% helix, 10% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AStructural maintenance of chromosomes protein 3protein123069% helix, 10% strandP47037

Pockets

10 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11020.510.8229empty
21710.500.7719empty
3550.420.8314empty
4830.400.7812empty
5680.390.7912empty

Compared structures

  • 7OGT · Folded elbow of cohesin · an experimental structure of the same protein · chain A against B, TM-score 0.44
  • 7OGT · Folded elbow of cohesin · an experimental structure of the same protein · chain A against B, TM-score 0.44
  • 4UX3 · Cohesin SMC3-HD:SCC1-N complex from yeast · an experimental structure of the same protein · chain A against A, TM-score 0.31
  • 4UX3 · cohesin Smc3-HD:Scc1-N complex from yeast · an experimental structure of the same protein · chain A against A, TM-score 0.31
  • 6ZZ6 · Cryo-EM structure of S.CEREVISIAE cohesin-SCC2-DNA complex · an experimental structure of the same protein · chain A against B, TM-score 0.30
  • 6ZZ6 · Cryo-EM structure of S.cerevisiae cohesin-Scc2-DNA complex · an experimental structure of the same protein · chain A against B, TM-score 0.30
  • 6QPW · Structural basis of cohesin ring opening · an experimental structure of the same protein · chain A against C, TM-score 0.28
  • 6QPW · Structural basis of cohesin ring opening · an experimental structure of the same protein · chain A against C, TM-score 0.28

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