MolNFT v1 · #311080 · protein
AlphaFold monomer V2.0 prediction for pre-mRNA-processing factor 19 (P32523)
P32523: “AlphaFold monomer V2.0 prediction for pre-mRNA-processing factor 19 (P32523)”. 3 pockets (best druggability 0.74). MolNFT v1 #311080 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P32523
- Type
- protein
- Length
- 503 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x473a866D01BaacC5B3b6058eD2e8CFa195DE4d05
- Molecule
- Pre-mRNA-processing factor 19
- UniProt
- P32523
- Pockets
- 3 · best druggability 0.74
Structure
1 distinct chain · 21% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA-processing factor 19 | protein | 503 | 21% helix, 35% strand | P32523 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 430 | 0.74 | 0.84 | 56 | empty |
| 2 | 62 | 0.54 | 0.88 | 23 | empty |
| 3 | 52 | 0.32 | 0.78 | 14 | empty |
Compared structures
- 4ZB4 · Spliceosome component · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 4ZB4 · Spliceosome component · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 5M8C · Spliceosome component · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 5M8C · Spliceosome component · an experimental structure of the same protein · chain A against A, TM-score 0.70
- 6BK8 · S. cerevisiae spliceosomal post-catalytic P complex · an experimental structure of the same protein · chain A against u, TM-score 0.64
- 6BK8 · S. cerevisiae spliceosomal post-catalytic P complex · an experimental structure of the same protein · chain A against u, TM-score 0.64
- 5MQ0 · Structure of a spliceosome remodeled for exon ligation · an experimental structure of the same protein · chain A against w, TM-score 0.64
- 5LJ5 · Overall structure of the yeast spliceosome immediately after branching. · an experimental structure of the same protein · chain A against w, TM-score 0.64
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P32523
- Elsewhere: UniProt P32523 · AlphaFold DB P32523
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