AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (P52503)

Structure

1 distinct chain · 14% helix, 16% strand (DSSP).

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 8RGR · Closed Complex I from murine liver · an experimental structure of the same protein · chain A against 7, TM-score 0.81
• 8PW6 · C respirasome from murine liver · an experimental structure of the same protein · chain A against 7, TM-score 0.81
• 7B93 · Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at… · an experimental structure of the same protein · chain A against R, TM-score 0.80
• 7AK5 · Cryo-EM structure of respiratory complex I in the deactive state from mus musculus at 3.2… · an experimental structure of the same protein · chain A against R, TM-score 0.79
• 7AK5 · Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2… · an experimental structure of the same protein · chain A against R, TM-score 0.79
• 6G2J · Mouse mitochondrial complex I in the active state · an experimental structure of the same protein · chain A against R, TM-score 0.78
• 6G2J · Mouse mitochondrial complex I in the active state · an experimental structure of the same protein · chain A against R, TM-score 0.78
• 7AK6 · Cryo-EM structure of ND6-P25L mutant respiratory complex I from mus musculus at 3.8 a · an experimental structure of the same protein · chain A against R, TM-score 0.78
• 6ZTQ · Cryo-EM structure of respiratory complex I from mus musculus inhibited by piericidin a at… · an experimental structure of the same protein · chain A against R, TM-score 0.78
• 6ZR2 · Cryo-EM structure of respiratory complex I in the active state from mus musculus at 3.1 a · an experimental structure of the same protein · chain A against R, TM-score 0.78
• 6G72 · Mouse mitochondrial complex I in the deactive state · an experimental structure of the same protein · chain A against R, TM-score 0.78
• 8IBE · Respiratory complex Peripheral Arm of CI, focus-refined map of type II, Wild type mouse… · an experimental structure of the same protein · chain A against R, TM-score 0.69

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P52503
• Elsewhere: UniProt P52503 · AlphaFold DB P52503