Research workbench

Co-crystallization of streptavidin-biotin complex with a lanthanide- ligand complex gives rise to a novel crystal form

Analyse Co-crystallization of streptavidin-biotin complex with a lanthanide- ligand… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4IRW
Type: protein
Length: 123 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Streptavidin
UniProt: P22629
Ligands: PDC, BTN, TB, NA
Pockets: 1 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 7% helix, 54% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Streptavidin	protein	123	7% helix, 54% strand	P22629

Ligands and binding sites

PDC · Pyridine-2,6-dicarboxylic acid · ligand · 12 copies · chains A
BTN · Biotin · ligand · chains A
TB · Terbium(iii) ion · metal · 5 copies · chains A
NA · Sodium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	85	0.48	0.82	18	BTN

Compared structures

4IRW · Co-crystallization of streptavidin-biotin complex with a lanthanide-ligand complex gives… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P22629
Elsewhere: RCSB PDB 4IRW · PDBe 4IRW · UniProt P22629

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.