UniProt P22629
Streptavidin (P22629)
Streptavidin (UniProt P22629): 439 experimental structures and 1 predicted model on GenesisL1, 48 ligands bound, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P22629
- Protein
- Streptavidin
- Experimental structures
- 439
- Predicted models
- 1
- Ligands
- 48
- Pockets
- 21 · 4 records with a druggable one
Structures
440 records of P22629 in the MolNFT archive: 439 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1DF8 | S45A mutant of streptavidin in complex with biotin | x-ray diffraction | A, B | — | — |
| 1DF8 | S45A mutant of streptavidin in complex with biotin | x-ray diffraction | A, B | — | — |
| 1HQQ | Miniprotein mp-2 (M9A) complex with streptavidin | x-ray diffraction | A, B, C, D | — | — |
| 1HQQ | Miniprotein mp-2 (M9A) complex with streptavidin | x-ray diffraction | A, B, C, D | — | — |
| 1HXL | Miniprotein mp-2 (V10A) complex with streptavidin | x-ray diffraction | A, B | — | — |
| 1HXL | Miniprotein mp-2 (V10A) complex with streptavidin | x-ray diffraction | A, B | — | — |
| 1HXZ | Miniprotein mp-2 complex with streptavidin | x-ray diffraction | A, B | — | — |
| 1HXZ | Miniprotein mp-2 complex with streptavidin | x-ray diffraction | A, B | — | — |
| 1HY2 | Miniprotein mp-1 complex with streptavidin | x-ray diffraction | A, B, C, D | — | — |
| 1HY2 | Miniprotein mp-1 complex with streptavidin | x-ray diffraction | A, B, C, D | — | — |
| 1I9H | Core streptavidin-bna complex | x-ray diffraction | A, B | — | — |
| 1I9H | Core streptavidin-bna complex | x-ray diffraction | A, B | — | — |
| 1KFF | An engineered streptavidin with improved affinity for the strep-tag II peptide: apo-SAM1 | x-ray diffraction | A, B, C, D | — | — |
| 1KFF | An engineered streptavidin with improved affinity for the strep-tag II peptide: apo-SAM1 | x-ray diffraction | A, B, C, D | — | — |
| 1KL3 | an engineered streptavidin with improved affinity for the strep-tag II peptide : SAm1-StrepII | x-ray diffraction | A, B, C, D | — | — |
| 1KL3 | An engineered streptavidin with improved affinity for the strep-tag II peptide : SAM1-strepii | x-ray diffraction | A, B, C, D | — | — |
| 1KL4 | AN ENGINEERED STREPTAVIDIN WITH IMPROVED AFFINITY FOR THE STREP-TAG II PEPTIDE : apo-SAM2 | x-ray diffraction | A, B, C, D | — | — |
| 1KL4 | An engineered streptavidin with improved affinity for the strep-tag II peptide : apo-SAM2 | x-ray diffraction | A, B, C, D | — | — |
| 1KL5 | an engineered streptavidin with improved affinity for the strep-tag II peptide : SAm2-StrepII | x-ray diffraction | A, B, C, D | — | — |
| 1KL5 | An engineered streptavidin with improved affinity for the strep-tag II peptide : SAM2-strepii | x-ray diffraction | A, B, C, D | — | — |
| 1LCV | streptavidin-norbiotin complex | x-ray diffraction | A, B | — | — |
| 1LCV | Streptavidin-norbiotin complex | x-ray diffraction | A, B | — | — |
| 1LCW | streptavidin-homobiotin complex | x-ray diffraction | A, B | — | — |
| 1LCW | Streptavidin-homobiotin complex | x-ray diffraction | A, B | — | — |
| 1LCZ | streptavidin-BCAP complex | x-ray diffraction | A, B | — | — |
| 1LCZ | Streptavidin-bcap complex | x-ray diffraction | A, B | — | — |
| 1MEP | Crystal Structure of Streptavidin Double Mutant S45A/D128A with Biotin: Cooperative Hydrogen-Bond… | x-ray diffraction | A, B, C, D | — | — |
| 1MEP | Crystal structure of streptavidin double mutant S45A/D128A with biotin: cooperative hydrogen-bond… | x-ray diffraction | A, B, C, D | — | — |
| 1MK5 | Wildtype Core-Streptavidin with Biotin at 1.4A. | x-ray diffraction | A, B | — | — |
| 1MK5 | Wildtype core-streptavidin with biotin at 1.4A. | x-ray diffraction | A, B | — | — |
| 1MM9 | Streptavidin Mutant with Insertion of Fibronectin Hexapeptide, including RGD | x-ray diffraction | A | — | — |
| 1MM9 | Streptavidin mutant with insertion of fibronectin hexapeptide, including rgd | x-ray diffraction | A | — | — |
| 1MOY | Streptavidin Mutant with Osteopontin Hexapeptide Insertion Including RGD | x-ray diffraction | A | — | — |
| 1MOY | Streptavidin mutant with osteopontin hexapeptide insertion including rgd | x-ray diffraction | A | — | — |
| 1N43 | Streptavidin Mutant N23A with biotin at 1.89A | x-ray diffraction | A, B, C, D | — | — |
| 1N43 | Streptavidin mutant N23A with biotin at 1.89A | x-ray diffraction | A, B, C, D | — | — |
| 1N4J | Streptavidin mutant N23A at 2.18A | x-ray diffraction | A | — | — |
| 1N4J | Streptavidin mutant N23A at 2.18A | x-ray diffraction | A | — | — |
| 1N7Y | Streptavidin mutant N23E at 1.96A | x-ray diffraction | A, B, C, D | — | — |
| 1N7Y | Streptavidin mutant N23E at 1.96A | x-ray diffraction | A, B, C, D | — | — |
| 1N9M | Streptavidin Mutant S27A with Biotin at 1.6A Resolution | x-ray diffraction | A, B, C, D | — | — |
| 1N9M | Streptavidin mutant S27A with biotin at 1.6A resolution | x-ray diffraction | A, B, C, D | — | — |
| 1N9Y | Streptavidin Mutant S27A at 1.5A Resolution | x-ray diffraction | A, B, C, D | — | — |
| 1N9Y | Streptavidin mutant S27A at 1.5A resolution | x-ray diffraction | A, B, C, D | — | — |
| 1NBX | Streptavidin Mutant Y43A at 1.70A Resolution | x-ray diffraction | A, B, C, D | — | — |
| 1NBX | Streptavidin mutant Y43A at 1.70A resolution | x-ray diffraction | A, B, C, D | — | — |
| 1NC9 | Streptavidin mutant Y43A with iminobiotin at 1.8A resolution | x-ray diffraction | A, B, C, D | — | — |
| 1NC9 | Streptavidin mutant Y43A with iminobiotin at 1.8A resolution | x-ray diffraction | A, B, C, D | — | — |
| 1NDJ | Streptavidin Mutant Y43F with Biotin at 1.81A Resolution | x-ray diffraction | A, B, C, D | — | — |
| 1NDJ | Streptavidin mutant Y43F with biotin at 1.81A resolution | x-ray diffraction | A, B, C, D | — | — |
| 1NQM | Structure of Savm-W120K, streptavidin mutant | x-ray diffraction | A, B, C, D | — | — |
| 1NQM | Structure of savm-W120K, streptavidin mutant | x-ray diffraction | A, B, C, D | — | — |
| 1PTS | Crystal structure and ligand binding studies of a screened peptide complexed with streptavidin | x-ray diffraction | A, B | — | — |
| 1PTS | Crystal structure and ligand binding studies of a screened peptide complexed with streptavidin | x-ray diffraction | A, B | — | — |
| 1RST | Complex between streptavidin and the strep-tag peptide | x-ray diffraction | B | — | — |
| 1RST | Complex between streptavidin and the strep-tag peptide | x-ray diffraction | B | — | — |
| 1RSU | Complex between streptavidin and the strep-tag II peptide | x-ray diffraction | B | — | — |
| 1RSU | Complex between streptavidin and the strep-tag II peptide | x-ray diffraction | B | — | — |
| 1RXH | Crystal structure of streptavidin mutant L124R (M1) complexed with biotinyl p-nitroanilide (BNI) | x-ray diffraction | A, B | — | — |
| 1RXH | Crystal structure of streptavidin mutant L124R (M1) complexed with biotinyl P-nitroanilide (bni) | x-ray diffraction | A, B | — | — |
380 records more on the page itself.
Ligands
- HL9 · 5-[(3~{A}~{S},4~{S},6~{A}~{R})-2-oxidanylidene-1,3, 3~{A},4,6,6~{A}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-(1-pyridin-4-ylpiperidin-4-yl)pentanamide · in 14 records
- BTN · Biotin · in 10 records
- KM3 · {N-(4-{bis[(pyridin-2-yl-kappaN)methyl]amino-kappaN}butyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}iron(3+) · in 9 records
- NH2 · Amino group · in 9 records
- 4IR · {N-(4-{[2-(amino-kappaN)ethyl]sulfamoyl-kappaN}phenyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}(chloro)[(1,2,3,4,5-eta)-1,2,3,4,5-pentamethylcyclopentadienyl]iridium(III) · in 7 records
- SO4 · Sulfate ion · in 6 records
- CU · Copper (II) ion · in 5 records
- CL · Chloride ion · in 4 records
- CU6 · [CuII(biot-et-dpea)]2+ · in 3 records
- IR · Iridium ion · in 3 records
- N9O · 5-[(3~{A}~{S},4~{S},6~{A}~{R})-2-oxidanylidene-1,3, 3~{A},4,6,6~{A}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[2-[6-(dimethylamino)-1,3-bis(oxidanylidene) benzo[de]isoquinolin-2-yl]ethyl]pentanamide · in 3 records
- IR3 · Iridium (III) ion · in 2 records
- JLL · (2R)-2-[5-[(3aS,4S,6aR)-2-oxidanylidene-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-3-[[(5Z,10Z,14Z,19Z)-15-[[[(2R)-2-[5-[(3aS,4S,6aR)-2-oxidanylidene-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-3-sulfo-propanoyl]amino]methyl]-1,4,21,23-tetrahydroporphyrin-5-yl]methylamino]-3-oxidanylidene-propane-1-sulfonic acid · in 2 records
- NA · Sodium ion · in 2 records
- QFY · {N-(2-{bis[(pyridin-2-yl-kappan)methyl]amino-kappan}ethyl)-5-[(3as,4s,6ar)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide}iron(3+) · in 2 records
- QG7 · N-(2-{bis[(pyridin-2-yl)methyl]amino}ethyl)-5-[(3as,4s, 6AR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide · in 2 records
- 6IR · 5-[(3~{A}~{S},4~{S},6~{A}~{R})-2-oxidanylidene-1,3, 3~{A},4,6,6~{A}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[4-(2-azanylethylsulfamoyl)phenyl]pentanamide · in 1 record
- 9CO · [cobr(appy)-biot]br · in 1 record
- 9RU · [1-[4-[[5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]methyl]-2,6-dimethyl-phenyl]-3-(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-1-ium-2-yl]-bis(chloranyl)ruthenium · in 1 record
- BN7 · 2-methylpropyl 5-[(3as,4s,6ar)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate · in 1 record
- BR · Bromide ion · in 1 record
- BYY · 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-selenopheno[3,4-d]imidazol-4-yl]pentanoic acid · in 1 record
- BZ4 · N-[(2H-1,3-benzodioxol-5-yl)methyl]-2-({[(2H-1,3-benzodioxol-5-yl)methyl][2-(chloromethyl)-1,3-oxazole-4-carbonyl]amino}methyl)-N-[(4-carbamoyl-1,3-oxazol-2-yl)methyl]-1,3-oxazole-4-carboxamide · in 1 record
- EYW · 5-[(3~{A}~{S},4~{S},6~{A}~{R})-2-oxidanylidene-1,3, 3~{A},4,6,6~{A}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[(3~{R})-pyrrolidin-3-yl]pentanamide · in 1 record
- HDO · 1-hydroxydodecan-4-one · in 1 record
- JCT · Biotinylated ruthenium cyclopentadienide · in 1 record
- K9D · 5-[(3~{A}~{S},4~{S},6~{A}~{R})-2-oxidanylidene-1,3, 3~{A},4,6,6~{A}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[2-[6-(3,4-dihydro-1~{H}-isoquinolin-2-yl)-1,3-bis(oxidanylidene)benzo[de]isoquinolin-2-yl]ethyl]pentanamide · in 1 record
- K9R · 5-[(3~{A}~{S},4~{S},6~{A}~{R})-2-oxidanylidene-1,3, 3~{A},4,6,6~{A}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[(1~{R},3~{S})-3-[3,5-bis(sulfanylmethyl)phenyl]-2,4-bis(oxidanylidene)cyclopentyl]pentanamide · in 1 record
- MN · Manganese (II) ion · in 1 record
- NOF · tert-butyl 7'-[5-[(3aS,4S,6aR)-2-oxidanylidene-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]-1-chloranyl-2,3,4,5,6-pentamethyl-spiro[1$l^{8}-iridapentacyclo[2.2.0.0^{1,3}.0^{1,5}.0^{2,6}]hexane-1,2'-3-aza-1-azonia-2$l^{8}-iridatricyclo[6.3.1.0^{4,12}]dodeca-1(11),4,6,8(12),9-pentaene]-3'-carboxylate · in 1 record
Experiment against prediction
- 5CSE chain A against the predicted model P22629: TM-score 0.99, RMSD 0.34 Å
- 5CSE chain B against the predicted model P22629: TM-score 0.99, RMSD 0.37 Å
- 1NBX chain A against the predicted model P22629: TM-score 0.99, RMSD 0.37 Å
- 1SWA chain A against the predicted model P22629: TM-score 0.99, RMSD 0.38 Å
- 9CSU chain A against the predicted model P22629: TM-score 0.99, RMSD 0.40 Å
- 1LCV chain B against the predicted model P22629: TM-score 0.99, RMSD 0.39 Å
- 1N7Y chain A against the predicted model P22629: TM-score 0.99, RMSD 0.39 Å
- 1LCZ chain B against the predicted model P22629: TM-score 0.99, RMSD 0.41 Å
- 6M9B chain D against the predicted model P22629: TM-score 0.99, RMSD 0.41 Å
- 1PTS chain B against the predicted model P22629: TM-score 0.99, RMSD 0.40 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.