GL1X · GenesisL1 explorer

Ligand · BTN

BTN · Biotin

BTN, Biotin (C10 H16 N2 O3 S, 244.3 g/mol), in the MolNFT structures on GenesisL1: bound in 27 records (23 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
BTN
Formula
C10 H16 N2 O3 S
Class
ligand
Structures
27
PDB entries
23

Binding sites

BTN in 27 structures; the first of them:

  • 6BI2 · Trastuzumab Fab D185A (Light Chain) Mutant Biotin Conjugation. · BTN L301 · binds ASP151, LYS188, HIS189, LYS190
  • 6M9B · Wild-type streptavidin in complex with biotin solved by native SAD with data collected at… · BTN A201 · binds ASN15, LEU17, SER19, TYR35, SER37, VAL39, GLY40, ASN41 and 10 more
  • 6NKP · EphA2 LBD in complex with bA-WLA-YSKbio peptide · BTN C14 · binds TRP43, LEU44, THR45, TYR48, THR132, PHE134
  • 7LA8 · O6 variable lymphocyte receptor ectodomain bound to 3-HSO3-Gal-4GlcNAc · BTN A201 · binds HIS109, THR110, GLU136, ASN145, ASN148, LYS150
  • 7ZZ1 · Cryo-EM structure of "CT react" conformation of Lactococcus lactis pyruvate carboxylase… · BTN B1201 · binds GLN537, ALA572, VAL576, ARG606, TYR613, GLY828, GLN829, ASN832 and 4 more
  • 8XL6 · Structure of human 3-methylcrotonyl-CoA carboxylase at apo-state (MCC-Apo) · BTN A801 · binds MET680, LYS681, VAL375, THR405, GLY406, PHE407, MET408, VAL409 and 5 more
  • 5L20 · Crystal structure of a clostripain (BT_0727) from bacteroides thetaiotaomicron atcc 29148… · BTN C401 · binds VAL402, LEU403
  • 5VYW · Crystal structure of lactococcus lactis pyruvate carboxylase · BTN A1202 · binds TYR467, MET470, ASN474, GLY475, PHE476, PRO477, ARG579, PHE580 and 2 more
  • 6AUL · Artificial metalloproteins containing a CO4O4 active site - 2XM-S112Y- B · BTN A201 · binds ASN23, LEU25, SER27, TYR43, SER45, VAL47, GLY48, ASN49 and 10 more
  • 6BI2 · Trastuzumab Fab D185A (light chain) mutant biotin conjugation. · BTN L301 · binds ASP151, LYS188, HIS189, LYS190
  • 6HDT · Crystal structure of short afifavidin - biotin complex · BTN A201 · binds ASN23, SER27, TYR43, ASN45, ALA47, PHE50, GLY51, TRP74 and 7 more
  • 6J6J · Biotin-bound streptavidin · BTN A5100 · binds SER27, TYR43, SER45, VAL47, GLY48, ASN49, TRP79, ALA86 and 6 more
  • 6M9B · Wild-type streptavidin in complex with biotin solved by native sad with data collected at… · BTN A201 · binds ASN15, LEU17, SER19, TYR35, SER37, VAL39, GLY40, ASN41 and 9 more
  • 6NJZ · EPHA2 lbd in complex with ysa-gsgsk-bio peptide · BTN C18 · binds THR132, TRP43, LEU44, THR45, HIS46, TYR48, THR132, PHE134
  • 6NKP · EPHA2 lbd in complex with ba-wla-yskbio peptide · BTN C14 · binds TRP43, LEU44, THR45, TYR48, THR132, PHE134
  • 6UC3 · Spectroscopic and structural characterization of a genetically encoded direct sensor for… · BTN A201 · binds ASN23, LEU25, SER27, TYR43, SER45, VAL47, GLY48, ASN49 and 9 more
  • 6UDC · Spectroscopic and structural characterization of a genetically encoded direct sensor for… · BTN A5001 · binds ASN23, LEU25, SER27, TYR43, SER45, VAL47, GLY48, ASN49 and 10 more

Residues it binds most

TRP 49, SER 49, ASN 57, LEU 56, ALA 52, THR 59, TYR 50, GLY 54, VAL 43, ASP 46 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol
  • SGA · 3-O-sulfo-beta-D-galactopyranose
  • MN · Manganese (II) ion
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • SO4 · Sulfate ion
  • GOL · Glycerol
  • CKC · (3S)-3,7-diaminoheptan-2-one
  • OAA · Oxaloacetate ion
  • MG · Magnesium ion
  • NA · Sodium ion
  • UNX · Unknown atom or ion
  • P33 · 3,6,9,12,15,18-hexaoxaicosane-1,20-diol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.