Research workbench

Crystal structure of epithelial adhesin 6 a domain (EPA6A) from candida glabrata in complex with GALA1-3GAL

Analyse Crystal structure of epithelial adhesin 6 a domain (EPA6A) from candida… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4COV
Type: protein
Length: 230 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Epithelial adhesin 6
UniProt: Q6FX55
Ligands: GAL, GLA, CA
Pockets: 1 · best druggability 0.31

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 39% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Epithelial adhesin 6	protein	230	6% helix, 39% strand	Q6FX55

Ligands and binding sites

GAL · beta-D-galactopyranose · sugar · chains A
GLA · alpha-D-galactopyranose · sugar · chains A
CA · Calcium ion · metal · chains A
ACT · Acetate ion · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	60	0.31	0.75	15	empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

4COV · Crystal Structure of Epithelial Adhesin 6 A domain (Epa6A) from Candida glabrata in… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6FX55
Elsewhere: RCSB PDB 4COV · PDBe 4COV · UniProt Q6FX55

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.