Research workbench
Crystal structure of A20 ZF7 in complex with linear tetraubiquitin
Analyse Crystal structure of A20 ZF7 in complex with linear tetraubiquitin in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3VUY
- Type
- protein
- Length
- 324 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Polyubiquitin-C; Tumor necrosis factor alpha-induced protein 3
- UniProt
- P0CG48, P21580
- Ligands
- ZN, K
Structure
x-ray diffraction · 4 distinct chains · 28% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, C, B | Polyubiquitin-C | protein | 76 | 20% helix, 33% strand | P0CG48 |
| D | Tumor necrosis factor alpha-induced protein 3 | protein | 33 | 36% helix, 6% strand | P21580 |
| F | Tumor necrosis factor alpha-induced protein 3 | protein | 31 | 29% helix, 6% strand | P21580 |
| E | Tumor necrosis factor alpha-induced protein 3 | protein | 32 | 41% helix, 6% strand | P21580 |
Ligands and binding sites
- ZN · Zinc ion · metal · 3 copies · chains A, D, C, F, B, E
- K · Potassium ion · metal · 3 copies · chains D, F, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
6 interfaces between chains.
- B–E · 634 Ų buried · 1 hydrogen bond · protein-protein
- A–D · 619 Ų buried · 2 hydrogen bonds · protein-protein
- C–F · 612 Ų buried · 3 hydrogen bonds · protein-protein
- C–B · 415 Ų buried · 1 hydrogen bond · protein-protein
- A–E · 360 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 3VUY · Crystal structure of A20 ZF7 in complex with linear tetraubiquitin · the same entry in another collection · chain E against E, TM-score 1.00
- P21580 · AlphaFold monomer V2.0 prediction for tumor necrosis factor alpha- induced protein 3… · a predicted model of the same protein · chain E against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0CG48
- Every structure of UniProt P21580
- Elsewhere: RCSB PDB 3VUY · PDBe 3VUY · UniProt P0CG48 · UniProt P21580
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