MolNFT v1 · #468988 · protein
AlphaFold monomer V2.0 prediction for tumor necrosis factor alpha- induced protein 3 (P21580)
P21580 · Tumor necrosis factor alpha-induced protein 3: “AlphaFold monomer V2.0 prediction for tumor necrosis factor alpha- induced protein 3 (P21580)”. 5 pockets (best druggability 0.64). MolNFT v1 #468988 on GenesisL1: 3D structure…
- Accession
- P21580
- Type
- protein
- Length
- 790 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x46EfCa788d03A3e879DAcDb96552AB8Bbc7e20b3
- Molecule
- Tumor necrosis factor alpha-induced protein 3
- UniProt
- P21580
- Pockets
- 5 · best druggability 0.64
Structure
1 distinct chain · 30% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tumor necrosis factor alpha-induced protein 3 | protein | 790 | 30% helix, 12% strand | P21580 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 417 | 0.64 | 0.78 | 62 | empty |
| 2 | 381 | 0.60 | 0.77 | 40 | empty |
| 3 | 334 | 0.53 | 0.73 | 25 | empty |
| 4 | 106 | 0.36 | 0.73 | 14 | empty |
| 5 | 75 | 0.32 | 0.74 | 17 | empty |
Compared structures
- 5LRX · Structure of A20 otu domain bound to ubiquitin · an experimental structure of the same protein · chain A against A, TM-score 0.44
- 5LRX · Structure of A20 OTU domain bound to ubiquitin · an experimental structure of the same protein · chain A against A, TM-score 0.44
- 3DKB · Crystal structure of A20, 2.5 ångström · an experimental structure of the same protein · chain A against A, TM-score 0.43
- 3DKB · Crystal Structure of A20, 2.5 angstrom · an experimental structure of the same protein · chain A against A, TM-score 0.43
- 2VFJ · Structure of the A20 ovarian tumour (otu) domain · an experimental structure of the same protein · chain A against A, TM-score 0.42
- 2VFJ · Structure of the A20 Ovarian Tumour (OTU) domain · an experimental structure of the same protein · chain A against A, TM-score 0.42
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P21580
- Elsewhere: UniProt P21580 · AlphaFold DB P21580
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