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Crystal structure of the complex of the carbohydrate recognition domain of human dc-sign with pseudo dimannoside mimic.

Analyse Crystal structure of the complex of the carbohydrate recognition domain of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2XR5
Type: protein
Length: 131 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: CD209 antigen
UniProt: Q9NNX6
Ligands: 07B, ETA, MAN, CA, CL

Structure

x-ray diffraction · 1 distinct chain · 25% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	CD209 antigen	protein	131	25% helix, 34% strand	Q9NNX6

Ligands and binding sites

07B · dimethyl (1S,2S,4S,5S)-4,5-dihydroxycyclohexane-1,2-dicarboxylate · ligand · chains A
ETA · Ethanolamine · ligand
MAN · alpha-D-mannopyranose · sugar · chains A
CA · Calcium ion · metal · 3 copies · chains A
CL · Chloride ion · ion · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

2XR5 · Crystal structure of the complex of the carbohydrate recognition domain of human DC-SIGN… · the same entry in another collection · chain A against A, TM-score 1.00
Q9NNX6 · AlphaFold monomer V2.0 prediction for CD209 antigen (Q9NNX6) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9NNX6
Elsewhere: RCSB PDB 2XR5 · PDBe 2XR5 · UniProt Q9NNX6

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