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Structure of a C-type carbohydrate-recognition domain (crd- 4) from the macrophage mannose receptor

Analyse Structure of a C-type carbohydrate-recognition domain (crd- 4) from the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1EGI
Type: protein
Length: 272 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Macrophage mannose receptor
UniProt: P22897
Ligands: CA

Structure

x-ray diffraction · 2 distinct chains · 20% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Macrophage mannose receptor	protein	129	20% helix, 27% strand	P22897
B	Macrophage mannose receptor	protein	143	20% helix, 27% strand	P22897

Ligands and binding sites

CA · Calcium ion · metal · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 70 Å² buried · 0 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

1EGI · Structure of a C-type carbohydrate-recognition domain (crd-4) from the macrophage mannose… · the same entry in another collection · chain A against A, TM-score 1.00
P22897 · AlphaFold monomer V2.0 prediction for macrophage mannose receptor 1 (P22897) · a predicted model of the same protein · chain B against A, TM-score 0.78

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P22897
Elsewhere: RCSB PDB 1EGI · PDBe 1EGI · UniProt P22897

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