Research workbench
Crystal structure of human leukotriene C4 synthase in complex with substrate glutathione
Analyse Crystal structure of human leukotriene C4 synthase in complex with substrate… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2UUH
- Type
- protein
- Length
- 150 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Leukotriene C4 synthase
- EC
- 4.4.1.20
- UniProt
- Q16873
- Ligands
- PLM, LMU, GSH, PAM, NI, SO4
Structure
x-ray diffraction · 1 distinct chain · 85% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Leukotriene C4 synthase (EC 4.4.1.20) | protein | 150 | 85% helix, 0% strand | Q16873 |
Ligands and binding sites
- PLM · Palmitic acid · ligand · 5 copies · chains A
- LMU · Dodecyl-alpha-D-maltoside · ligand · chains A
- GSH · Glutathione · ligand · chains A
- PAM · Palmitoleic acid · ligand · chains A
- NI · Nickel (II) ion · metal · 2 copies · chains A
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 2UUH · Crystal structure of Human Leukotriene C4 Synthase in complex with substrate glutathione · the same entry in another collection · chain A against A, TM-score 1.00
- Q16873 · AlphaFold monomer V2.0 prediction for leukotriene C4 synthase (Q16873) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q16873
- Elsewhere: RCSB PDB 2UUH · PDBe 2UUH · UniProt Q16873
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.