UniProt Q16873
Q16873
Q16873 (UniProt Q16873): 26 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q16873
- Experimental structures
- 26
- Predicted models
- 1
- Ligands
- 3
Structures
27 records of Q16873 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2PNO | Crystal structure of human leukotriene C4 synthase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 2PNO | Crystal structure of human leukotriene C4 synthase | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 2UUH | Crystal structure of Human Leukotriene C4 Synthase in complex with substrate glutathione | x-ray diffraction | A | — | — |
| 2UUH | Crystal structure of human leukotriene C4 synthase in complex with substrate glutathione | x-ray diffraction | A | — | — |
| 2UUI | Crystal structure of Human Leukotriene C4 Synthase | x-ray diffraction | A | — | — |
| 2UUI | Crystal structure of human leukotriene C4 synthase | x-ray diffraction | A | — | — |
| 3B29 | Human leukotriene C4 synthase in complex with dodecyl-beta-D-selenomaltoside | x-ray diffraction | A | — | — |
| 3B29 | Human leukotriene C4 synthase in complex with dodecyl-beta-D- selenomaltoside | x-ray diffraction | A | — | — |
| 3HKK | Structure of human Leukotriene C4 synthase in complex with glutathione sulfonate | x-ray diffraction | A | — | — |
| 3HKK | Structure of human leukotriene C4 synthase in complex with glutathione sulfonate | x-ray diffraction | A | — | — |
| 3LEO | Structure of human Leukotriene C4 synthase mutant R31Q in complex with glutathione | x-ray diffraction | A | — | — |
| 3LEO | Structure of human leukotriene C4 synthase mutant R31Q in complex with glutathione | x-ray diffraction | A | — | — |
| 3PCV | Crystal structure analysis of human leukotriene C4 synthase at 1.9 angstrom resolution | x-ray diffraction | A | — | — |
| 3PCV | Crystal structure analysis of human leukotriene C4 synthase at 1.9 ångström resolution | x-ray diffraction | A | — | — |
| 4J7T | Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | x-ray diffraction | A | — | — |
| 4J7T | Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | x-ray diffraction | A | — | — |
| 4J7Y | Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | x-ray diffraction | A | — | — |
| 4J7Y | Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | x-ray diffraction | A | — | — |
| 4JC7 | Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | x-ray diffraction | A | — | — |
| 4JC7 | Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | x-ray diffraction | A | — | — |
| 4JCZ | Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | x-ray diffraction | A | — | — |
| 4JCZ | Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | x-ray diffraction | A | — | — |
| 4JRZ | Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | x-ray diffraction | A | — | — |
| 4JRZ | Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | x-ray diffraction | A | — | — |
| 5HV9 | Human LTC4S mutant-S36E | x-ray diffraction | A | — | — |
| 6R7D | Crystal structure of LTC4S in complex with AZ13690257 | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | JUQ, NI, PLM | — |
| Q16873 | AlphaFold monomer V2.0 prediction for leukotriene C4 synthase (Q16873) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3B29 chain A against the predicted model Q16873: TM-score 0.99, RMSD 0.33 Å
- 3B29 chain A against the predicted model Q16873: TM-score 0.99, RMSD 0.33 Å
- 3PCV chain A against the predicted model Q16873: TM-score 0.99, RMSD 0.38 Å
- 3PCV chain A against the predicted model Q16873: TM-score 0.99, RMSD 0.38 Å
- 2PNO chain A against the predicted model Q16873: TM-score 0.99, RMSD 0.50 Å
- 2PNO chain A against the predicted model Q16873: TM-score 0.99, RMSD 0.50 Å
- 3HKK chain A against the predicted model Q16873: TM-score 0.99, RMSD 0.56 Å
- 3HKK chain A against the predicted model Q16873: TM-score 0.99, RMSD 0.56 Å
- 4JCZ chain A against the predicted model Q16873: TM-score 0.99, RMSD 0.40 Å
- 4JCZ chain A against the predicted model Q16873: TM-score 0.99, RMSD 0.40 Å
Elsewhere
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