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Crystal structure of human FGF23

Analyse Crystal structure of human FGF23 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2P39
Type: protein
Length: 142 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fibroblast growth factor 23
UniProt: Q9GZV9
Ligands: GU4, YYJ

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fibroblast growth factor 23	protein	142	6% helix, 35% strand	Q9GZV9

Ligands and binding sites

GU4 · 2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose · ligand · chains A
YYJ · 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

2P39 · Crystal structure of human FGF23 · the same entry in another collection · chain A against A, TM-score 1.00
Q9GZV9 · AlphaFold monomer V2.0 prediction for fibroblast growth factor 23 (Q9GZV9) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9GZV9
Elsewhere: RCSB PDB 2P39 · PDBe 2P39 · UniProt Q9GZV9

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