Ligand · GU4
GU4 · 2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose
GU4, 2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose (C6 H12 O18 S4, 500.4 g/mol), in the MolNFT structures on GenesisL1: bound in 12 records (8 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…
- Component
- GU4
- Formula
- C6 H12 O18 S4
- Class
- ligand
- Structures
- 12
- PDB entries
- 8
Binding sites
GU4 in 12 structures; the first of them:
- 7LRF · Netrin-1 in complex with SOS · GU4 K1 · binds ARG353, PHE354, ASN355, VAL369, ARG447, SER448, PRO449, ILE450
- 7NE0 · Structure of the ternary complex between Netrin-1, Repulsive-Guidance Molecule-B (RGMB)… · GU4 I1 · binds HIS92
- 7NE1 · Structure of the complex between Netrin-1 and its receptor Neogenin · GU4 G1 · binds SER90, CYS91, HIS92, LEU93, LYS101
- 7PGN · HHP-C in complex with glycosaminoglycan mimic SOS · GU4 E1 · binds LYS277, GLY278, ARG514, HIS550, LYS569
- 8CKL · Semaphorin-5A TSR 3-4 domains in complex with sucrose octasulfate (SOS) · GU4 H1 · binds LYS705, THR732, LYS734, GLY746, ARG747, ARG749
- 8HUE · Crystal structure of FGF2-M2 mutant - D28E/C78I/C96I/S137P · GU4 D1 · binds ASN36, LEU127, LYS128, ARG129, LYS134, LYS138, ALA145
- 8RMJ · Drosophila Semaphorin 2b in complex with glycosaminoglycan mimic SOS · GU4 F1 · binds LYS61, HIS63, ALA531, MET532, CYS533, ALA534, ARG535, ARG559 and 1 more
- 7LRF · Netrin-1 in complex with sos · GU4 K1 · binds ARG353, PHE354, ASN355, ARG447, SER448, PRO449, ILE450
- 7NE0 · Structure of the ternary complex between netrin-1, repulsive-guidance molecule-B (rgmb)… · GU4 I1 · binds HIS92
- 7NE1 · Structure of the complex between netrin-1 and its receptor neogenin · GU4 G1 · binds CYS91, HIS92, LEU93, LYS101
- 7PGK · Hhip-N, the N-terminal domain of the hedgehog-interacting protein (hhip), in complex with… · GU4 C1 · binds PRO44, PRO45, LYS46, ARG47
- 7PGN · Hhp-C in complex with glycosaminoglycan mimic sos · GU4 E1 · binds GLY278, ARG514, HIS550, LYS569
Residues it binds most
ARG 20, LYS 15, HIS 12, GLY 7, PRO 4, ASN 4, ALA 2, CYS 3, GLN 3, LEU 3 (residue and the binding sites it lines).
Found with
- YYJ · 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose
- CA · Calcium ion
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
- BMA · beta-D-mannopyranose
- NA · Sodium ion
- MAN · alpha-D-mannopyranose
- CL · Chloride ion
- NO3 · Nitrate ion
- SO4 · Sulfate ion
- EDO · 1,2-ethanediol
- GOL · Glycerol
- NHE · 2-[N-cyclohexylamino]ethane sulfonic acid
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