Research workbench
Solution structure of the complex between E.COLI nusa-AR2 and rnap- actd
Analyse Solution structure of the complex between E.COLI nusa-AR2 and rnap- actd in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2JZB
- Type
- protein
- Length
- 151 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DNA-directed RNA polymerase subunit alpha; Transcription elongation protein nusa
- EC
- 2.7.7.6
- UniProt
- P0A7Z4, P0AFF6
- Pockets
- 2 · best druggability 0.31
Structure
solution nmr · 2 distinct chains · 51% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA-directed RNA polymerase subunit alpha (EC 2.7.7.6) | protein | 81 | 47% helix, 2% strand | P0A7Z4 |
| B | Transcription elongation protein nusa | protein | 70 | 56% helix, 0% strand | P0AFF6 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 53 | 0.31 | 0.76 | 13 | empty |
| 2 | 66 | 0.30 | 0.74 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 359 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 2JZB · Solution structure of the complex between E.coli NusA-AR2 and RNAP-aCTD · the same entry in another collection · chain A against A, TM-score 1.00
- P0AFF6 · AlphaFold monomer V2.0 prediction for transcription TERMINATION/ANTITERMINATION protein… · a predicted model of the same protein · chain B against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A7Z4
- Every structure of UniProt P0AFF6
- Elsewhere: RCSB PDB 2JZB · PDBe 2JZB · UniProt P0A7Z4 · UniProt P0AFF6
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